Recombinant Human CHRM4 Protein

• Cat.No.: CHRM4-1274H
• Product Overview: Human CHRM4 full-length ORF (NP_000732.2) recombinant protein without tag.

Specification

• Description: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 53 kDa
• AA Sequence: MANFTPVNGSSGNQSVRLVTSSSHN RYETVEMVFIATVTGSLSLVTVVGN ILVMLSIKVNRQLQTVNNYFLFSLA CADLIIGAFSMNLYTVYIIKGYWPL GAVVCDLWLALDYVVSNASVMNLLI ISFDRYFCVTKPLTYPARRTTKMAG LMIAAAWVLSFVLWAPAILFWQFVV GKRTVPDNQCFIQFLSNPAVTFGTA IAAFYLPVVIMTVLYIHISLASRSR VHKHRPEGPKEKKAKTLAFLKSPLM KQSVKKPPPGEAAREELRNGKLEEA PPPALPPPPRPVADKDTSNESSSGS ATQNTKERPATELSTTEATTPAMPA PPLQPRALNPASRWSKIQIVTKQTG NECVTAIEIVPATPAGMRPAANVAR KFASIARNQVRKKRQMAARERKVTR TIFAILLAFILTWTPYNVMVLVNTF CQSCIPDTVWSIGYWLCYVNSTINP ACYALCNATFKKTFRHLLLCQYRNI GTAR
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: CHRM4 cholinergic receptor, muscarinic 4 [ Homo sapiens ]
• Official Symbol: CHRM4
• Synonyms: CHRM4; cholinergic receptor, muscarinic 4; muscarinic acetylcholine receptor M4; acetylcholine receptor; muscarinic 4; acetylcholine receptor, muscarinic 4; HM4; M4R
• Gene ID: 1132
• mRNA Refseq: NM_000741
• Protein Refseq: NP_000732
• MIM: 118495
• UniProt ID: P08173