Recombinant Human CHST11 Protein, GST-Tagged

• Cat.No.: CHST11-1295H
• Product Overview: Human CHST11 partial ORF (NP_060883, 230 a.a. - 337 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 37.62 kDa
• AA Sequence: RKGDDVKFEEFVAYLIDPHTQREEP FNEHWQTVYSLCHPCHIHYDLVGKY ETLEEDSNYVLQLAGVGSYLKFPTY AKSTRTTDEMTTEFFQNISSEHQTQ LYEVYKLD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 [ Homo sapiens ]
• Official Symbol: CHST11
• Synonyms: CHST11; carbohydrate (chondroitin 4) sulfotransferase 11; carbohydrate sulfotransferase 11; C4ST; C4St 1; C4ST1; HSA269537; C4S-1; IgH/CHST11 fusion; chondroitin 4-O-sulfotransferase 1; C4ST-1; FLJ41682; DKFZp667A035
• Gene ID: 50515
• mRNA Refseq: NM_001173982
• Protein Refseq: NP_001167453
• MIM: 610128
• UniProt ID: Q9NPF2