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Recombinant Human CKMT2 Protein, GST-tagged

Cat.No. : CKMT2-1401H
Product Overview : Human CKMT2 full-length ORF ( AAH29140, 1 a.a. - 419 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 71.83 kDa
AA Sequence : MASIFSKLLTGRNASLLFATMGTSV LTTGYLLNRQKVCAEVREQPRLFPP SADYPDLRKHNNCMAECLTPAIYAK LRNKVTPNGYTLDQCIQTGVDNPGH PFIKTVGMVAGDEESYEVFADLFDP VIKLRHNGYDPRVMKHTTDLDASKI TQGQFDEHYVLSSRVRTGRSIRGLS LPPACTRAERREVENVAITALEGLK GDLAGRYYKLSEMTEQDQQRLIDDH FLFDKPVSPLLTCAGMARDWPDARG IWHNYDKTFLIWINEEDHTRVISME KGGNMKRVFERFCRGLKEVERLIQE RGWEFMWNERLGYILTCPSNLGTGL RAGVHVRIPKLSKDPRFSKILENLR LQKRGTGGVDTAAVADVYDISNIDR IGRSEVELVQIVIDGVNYLVDCEKK LERGQDIKVPPPLPQFGKK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) [ Homo sapiens ]
Official Symbol : CKMT2
Synonyms : CKMT2; creatine kinase, mitochondrial 2 (sarcomeric); creatine kinase S-type, mitochondrial; SMTCK; S-MtCK; mib-CK; basic-type mitochondrial creatine kinase; sarcomeric mitochondrial creatine kinase;
Gene ID : 1160
mRNA Refseq : NM_001099735
Protein Refseq : NP_001093205
MIM : 123295
UniProt ID : P17540

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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