Recombinant Human CLDN4 Protein, GST-tagged
Cat.No. : | CLDN4-1443H |
Product Overview : | Human CLDN4 full-length ORF ( AAH00671, 1 a.a. - 209 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 48.73 kDa |
AA Sequence : | MASMGLQVMGIALAVLGWLAVMLCC ALPMWRVTAFIGSNIVTSQTIWEGL WMNCVVQSTGQMQCKVYDSLLALPQ DLQAARALVIISIIVAALGVLLSVV GGKCTNCLEDESAKAKTMIVAGVVF LLAGLMVIVPVSWTAHNIIQDFYNP LVASGQKREMGASLYVGWAASGLLL LGGGLLCCNCPPRTDKPYSAKYSAA RSAAASNYV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CLDN4 claudin 4 [ Homo sapiens ] |
Official Symbol : | CLDN4 |
Synonyms : | CLDN4; claudin 4; CPETR, CPETR1; claudin-4; Clostridium perfringens enterotoxin receptor 1; CPE R; hCPE R; WBSCR8; Williams Beuren syndrome chromosomal region 8 protein; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein; CPER; CPE-R; CPETR; CPETR1; hCPE-R; |
Gene ID : | 1364 |
mRNA Refseq : | NM_001305 |
Protein Refseq : | NP_001296 |
MIM : | 602909 |
UniProt ID : | O14493 |
Products Types
◆ Recombinant Protein | ||
CLDN4-150H | Recombinant Human CLDN4 Protein, Myc/DDK-tagged | +Inquiry |
CLDN4-1733M | Recombinant Mouse CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLDN4-612H | Recombinant Human CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLDN4-722R | Recombinant Rhesus Macaque CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cldn4-901M | Recombinant Mouse Cldn4 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CLDN4-7462HCL | Recombinant Human CLDN4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionInhibiting CLDN4 function could enhance the efficacy of existing cancer therapies and potentially lead to the development of new treatment strategies.
CLDN4 is involved in regulating the entry of certain pathogens into host cells, making it a potential target for the development of antiviral and antibacterial therapies.
Research is underway to explore the potential of targeting CLDN4 to modulate tissue barrier function and alleviate the symptoms of autoimmune diseases.
Monitoring CLDN4 levels and function may provide valuable insights into the progression of IBD and help in the development of targeted therapies.
CLDN4 is also being studied in the context of kidney disease, skin disorders, and neurodegenerative diseases due to its role in maintaining tissue barrier function.
Customer Reviews (3)
Write a reviewThe CLDN4 protein showcases outstanding quality, ensuring its suitability for addressing my experimental requirements effectively.
the manufacturer's dedication to excellent technical support assures me that any challenges or obstacles I encounter will be swiftly resolved.
Its top-notch purity and integrity instill confidence in obtaining precise and reliable data, thereby enabling significant advancements in my research.
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