Recombinant Human CLPP Protein, GST-tagged
Cat.No. : | CLPP-1512H |
Product Overview : | Human CLPP full-length ORF ( NP_006003.1, 1 a.a. - 277 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 56.6 kDa |
AA Sequence : | MWPGILVGGARVASCRYPALGPRLA AHFPAQRPPQRTLQNGLALQRCLHA TATRALPLIPIVVEQTGRGERAYDI YSRLLRERIVCVMGPIDDSVASLVI AQLLFLQSESNKKPIHMYINSPGGV VTAGLAIYDTMQYILNPICTWCVGQ AASMGSLLLAAGTPGMRHSLPNSRI MIHQPSGGARGQATDIAIQAEEIMK LKKQLYNIYAKHTKQSLQVIESAME RDRYMSPMEAQEFGILDKVLVHPPQ DGEDEPTLVQKEPVEAAPAAEPVPA ST |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CLPP ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) [ Homo sapiens ] |
Official Symbol : | CLPP |
Synonyms : | CLPP; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli); ClpP (caseinolytic protease, ATP dependent, proteolytic subunit, E. coli) homolog , ClpP caseinolytic protease, ATP dependent, proteolytic subunit homolog (E. coli); putative ATP-dependent Clp protease proteolytic subunit, mitochondrial; ATP dependent protease ClpAP (E. coli); proteolytic subunit; human; endopeptidase Clp; ATP-dependent protease ClpAP, proteolytic subunit, human; ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit; ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog; |
Gene ID : | 8192 |
mRNA Refseq : | NM_006012 |
Protein Refseq : | NP_006003 |
MIM : | 601119 |
UniProt ID : | Q16740 |
Products Types
◆ Lysates | ||
CLPP-7434HCL | Recombinant Human CLPP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTargeting CLPP therapeutically could offer potential in diseases related to mitochondrial dysfunction and aging.
CLPP activity is tightly regulated to ensure balanced protein turnover in mitochondria.
Dysregulation of CLPP is linked to various diseases, including mitochondrial disorders.
It helps in degrading misfolded or damaged proteins, maintaining mitochondrial function.
Proper functioning of CLPP is vital for mitochondrial health and energy production.
CLPP levels and activity are associated with aging, influencing cellular senescence and longevity.
CLPP plays a crucial role in mitochondrial protein degradation and quality control.
Customer Reviews (3)
Write a reviewVery high purity level.
Worked excellently in experiments.
Product was well packaged.
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