Recombinant Human CLSTN1 Protein, GST-tagged

• Cat.No.: CLSTN1-1518H
• Product Overview: Human CLSTN1 full-length ORF ( AAH33902.1, 1 a.a. - 971 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 135.1 kDa
• AA Sequence: MLRRPAPALAPAARLLLAGLLCGGG VWAARVNKHKPWLEPTYHGIVTEND NTVLLDPPLIALDKDAPLRFAGEIC GFKIHGQNVPFDAVVVDKSTGEGVI RSKEKLDCELQKDYSFTIQAYDCGK GPDGTNVKKSHKATVHIQVNDVNEY APVFKEKSYKATVIEGKQYDSILRV EAVDADCSPQFSQICSYEIITPDVP FTVDKDGYIKNTEKLNYGKEHQYKL TVTAYDCGKKRATEDVLVKISIKPT CTPGWQGWNNRIEYEPGTGALAVFP NIHLETCDEPVASVQATVELETSHI GKGCDRDTYSEKSLHRLCGAAAGTA ELLPSPSGSLNWTMGLPTDNGHDSD QVFEFNGTQAVRIPDGVVSVSPKEP FTISVWMRHGPFGRKKETILCSSDK TDMNRHHYSLYVHGCRLIFLFRQDP SEEKKYRPAEFHWKLNQVCDEEWHH YVLNVEFPSVTLYADGTSHEPFSVT EDYPLHPSKIETQLVVGACWQEFSG VENDNETEPVTVACAGGDLHMTQFF RGNLAGLTLRSGKLADKKVIDCLYT CKEGLDLQVLEDSGRGVQIQAHRSQ LVLTLEGEDLGELDKAMQHISYLNS RQFPTPGIRRLKITSTIKCFNEATC ISVPPVDGYVMVLQPEEPKISLSGV HHFARAASEFESSEGVFLFPELRII STITREVEPEGDGAEDPTVQESLVS EEIVHDLDTCEVTVEGEELNHEQES LEVDMARLQQKGIEVSSSELGMTFT GVDTMASYEEVLHLLRYRNWHARSL LDRKFKLICSELNGRYISNEFKVEV NVIHTANPMEHANHMAAQPQFVHPE HRSFVDLSGHNLANPHPFAVVHSTA TVVIVVCVSSLVFMIILGVFRIRAA HRRTMRDQDTGKENEMDWDDSALTI TVNPMETYEDQHSSEEEEEEEEEEE SEDGEEEDDITSAESESSEEEEGEQ GDPQNATRQQQLEWDDSTLSY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CLSTN1 calsyntenin 1 [ Homo sapiens ]
• Official Symbol: CLSTN1
• Synonyms: CLSTN1; calsyntenin 1; calsyntenin-1; cadherin related family member 12; CDHR12; CSTN1; KIAA0911; alcadein-alpha; alcadein alpha 1; non-classical cadherin XB31alpha; cadherin-related family member 12; non-classical cadherin XB31alpha1; alzheimer-related cadherin-like protein; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2; FLJ32258
• Gene ID: 22883
• mRNA Refseq: NM_001009566
• Protein Refseq: NP_001009566
• MIM: 611321
• UniProt ID: O94985