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Recombinant Human CRYGD Protein, GST-tagged

Cat.No. : CRYGD-1940H
Product Overview : Human CRYGD full-length ORF ( NP_008822.2, 1 a.a. - 174 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 47.1 kDa
AA Sequence : MGKITLYEDRGFQGRHYECSSDHPN LQPYLSRCNSARVDSGCWMLYEQPN YSGLQYFLRRGDYADHQQWMGLSDS VRSCRLIPHSGSHRIRLYEREDYRG QMIEFTEDCSCLQDRFRFNEIHSLN VLEGSWVLYELSNYRGRQYLLMPGD YRRYQDWGATNARVGSLRRVIDFS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CRYGD crystallin, gamma D [ Homo sapiens ]
Official Symbol : CRYGD
Synonyms : CRYGD; crystallin, gamma D; CRYG4; gamma-crystallin D; gamma crystallin 4; gamma-D-crystallin; gamma-crystallin 4; CCP; CACA; CCA3; cry-g-D;
Gene ID : 1421
mRNA Refseq : NM_006891
Protein Refseq : NP_008822
MIM : 123690
UniProt ID : P07320

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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