Active Recombinant Human CSNK1D Protein, GST-tagged

• Cat.No.: CSNK1D-1991H
• Product Overview: Human CSNK1D (NP_001884.2, 1 a.a. - 294 a.a.) partial recombinant protein with GST tag expressed in Escherichia coli.

Specification

• Description: This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Liquid
• Bio-activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: CKtide. ATP: 100 uM.
• Molecular Mass: 61 kDa
• Purity: 64 % by SDS-PAGE/CBB staining
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)

Gene Information

• Gene Name: CSNK1D casein kinase 1, delta [ Homo sapiens ]
• Official Symbol: CSNK1D
• Synonyms: CSNK1D; casein kinase 1, delta; casein kinase I isoform delta; CKID; CKIdelta; HCKID; CKId; CKI-delta; tau-protein kinase CSNK1D
• Gene ID: 1453
• mRNA Refseq: NM_001893
• Protein Refseq: NP_001884
• MIM: 600864
• UniProt ID: P48730