Recombinant Human CST4 Protein, GST-tagged

• Cat.No.: CST4-2027H
• Product Overview: Human CST4 full-length ORF ( NP_001890.1, 1 a.a. - 141 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 42.6 kDa
• AA Sequence: MARPLCTLLLLMATLAGALASSSKE ENRIIPGGIYDADLNDEWVQRALHF AISEYNKATEDEYYRRPLQVLRARE QTFGGVNYFFDVEVGRTICTKSQPN LDTCAFHEQPELQKKQLCSFEIYEV PWEDRMSLVNSRCQEA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CST4 cystatin S [ Homo sapiens ]
• Official Symbol: CST4
• Synonyms: CST4; cystatin S; cystatin-S; cystatin 4; cystatin-4; cystatin-SA-III; salivary acidic protein 1; MGC71923
• Gene ID: 1472
• mRNA Refseq: NM_001899
• Protein Refseq: NP_001890
• MIM: 123857
• UniProt ID: P01036