Recombinant Human CTLA4 Protein, DDK/His-tagged
Cat.No. : | CTLA4-344H |
Product Overview : | Recombinant Human CTLA4(Ala37-Phe162), transcript variant 1, fused with DDK/His tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Source : | HEK293 |
Species : | Human |
Tag : | DDK/His |
Form : | 1 x PBS, pH7.4, 10% glycerol |
Molecular Mass : | 16 kDa |
Protein length : | Ala37-Phe162 |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | CTLA4 cytotoxic T-lymphocyte-associated protein 4 [ Homo sapiens ] |
Official Symbol : | CTLA4 |
Synonyms : | CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease 3 , CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28; CD152; GSE; ICOS; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; GRD4; CTLA-4; IDDM12; CELIAC3; |
Gene ID : | 1493 |
mRNA Refseq : | NM_005214 |
Protein Refseq : | NP_005205 |
UniProt ID : | P16410 |
Products Types
◆ Recombinant Protein | ||
Ctla4-651H | Recombinant Human Ctla4 Protein, IgG2a Fc-tagged | +Inquiry |
Ctla4-06M | Active Recombinant Mouse Ctla4 Protein, hIgG/His-tagged | +Inquiry |
CTLA4-654M | Recombinant Mouse CTLA4 Protein, Fc-tagged | +Inquiry |
CTLA4-2075H | Recombinant Human CTLA4 Protein, GST-tagged | +Inquiry |
CTLA4-653M | Recombinant Mouse CTLA4 Protein | +Inquiry |
◆ Lysates | ||
CTLA4-1047CCL | Recombinant Cynomolgus CTLA4 cell lysate | +Inquiry |
CTLA4-2179MCL | Recombinant Mouse CTLA4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1712 | CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit | +Inquiry |
Kit-1713 | CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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