Active Recombinant Human CTLA4 protein, Twin Strep-tagged
Cat.No. : | CTLA4-2235H |
Product Overview : | Recombinant Human CTLA4(Ala 37 - Phe 162) fused with Twin Strep tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Twin Strep |
Predicted N Terminal : | Ala 37 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD80 /B7-1 Protein, With C-Fc Tag at 2 μg/mL ( 100 μl/well ) can bind Recombinant Human CTLA4 /CD152 Protein, With C-Twin Strep Tag with a linear range of 1-20 ng/mL.Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human B7-2 / CD86 Protein, With C-Fc Tag at 2 μg/mL ( 100 μl/well ) can bind Recombinant Human CTLA4 /CD152 Protein, With C-Twin Strep Tag with a linear range of 1-20 ng/mL. |
Molecular Mass : | Has a calculated MW of 16.5 kDa. DTT-reduced Protein migrates as 21-26 kDa in SDS-PAGE due to glycosylation. |
Protein length : | Ala 37 - Phe 162 |
Endotoxin : | Less than 1.0 EU per μg of the rh CTLA4 /CD152,twin strep tag by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade). |
Gene Name : | CTLA4 cytotoxic T-lymphocyte-associated protein 4 [ Homo sapiens ] |
Official Symbol : | CTLA4 |
Synonyms : | CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease 3 , CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28; CD152; GSE; ICOS; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; GRD4; CTLA-4; IDDM12; CELIAC3; |
Gene ID : | 1493 |
mRNA Refseq : | NM_005214 |
Protein Refseq : | NP_005205 |
MIM : | 123890 |
UniProt ID : | P16410 |
Chromosome Location : | 2q33 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; |
Function : | protein binding; |
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◆ Lysates | ||
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◆ Assay kits | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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