Recombinant Human CTSF Protein, GST-tagged
Cat.No. : | CTSF-2105H |
Product Overview : | Human CTSF full-length ORF ( NP_003784.2, 1 a.a. - 484 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
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Description : | Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 79.8 kDa |
AA Sequence : | MAPWLQLLSLLGLLPGAVAAPAQPR AASFQAWGPPSPELLAPTRFALEMF NRGRAAGTRAVLGLVRGRVRRAGQG SLYSLEATLEEPPCNDPMVCRLPVS KKTLLCSFQVLDELGRHVLLRKDCG PVDTKVPGAGEPKSAFTQGSAMISS LSQNHPDNRNETFSSVISLLNEDPL SQDLPVKMASIFKNFVITYNRTYES KEEARWRLSVFVNNMVRAQKIQALD RGTAQYGVTKFSDLTEEEFRTIYLN TLLRKEPGNKMKQAKSVGDLAPPEW DWRSKGAVTKVKDQGMCGSCWAFSV TGNVEGQWFLNQGTLLSLSEQELLD CDKMDKACMGGLPSNAYSAIKNLGG LETEDDYSYQGHMQSCNFSAEKAKV YINDSVELSQNEQKLAAWLAKRGPI SVAINAFGMQFYRHGISRPLRPLCS PWLIDHAVLLVGYGNRSDVPFWAIK NSWGTDWGEKGYYYLHRGSGACGVN TMASSAVVD |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CTSF cathepsin F [ Homo sapiens ] |
Official Symbol : | CTSF |
Synonyms : | CTSF; cathepsin F; CATSF; CLN13; |
Gene ID : | 8722 |
mRNA Refseq : | NM_003793 |
Protein Refseq : | NP_003784 |
MIM : | 603539 |
UniProt ID : | Q9UBX1 |
Products Types
◆ Recombinant Protein | ||
CTSF-05H | Active Recombinant Human CTSF Protein, His-tagged | +Inquiry |
CTSF-2066M | Recombinant Mouse CTSF Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctsf-8182M | Recombinant Mouse Ctsf protein, His & T7-tagged | +Inquiry |
CTSF-15903H | Recombinant Human CTSF, His-tagged | +Inquiry |
CTSF-4778Z | Recombinant Zebrafish CTSF | +Inquiry |
◆ Lysates | ||
CTSF-420HCL | Recombinant Human CTSF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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