Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human CTSF Protein, GST-tagged

Cat.No. : CTSF-2105H
Product Overview : Human CTSF full-length ORF ( NP_003784.2, 1 a.a. - 484 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 79.8 kDa
AA Sequence : MAPWLQLLSLLGLLPGAVAAPAQPR AASFQAWGPPSPELLAPTRFALEMF NRGRAAGTRAVLGLVRGRVRRAGQG SLYSLEATLEEPPCNDPMVCRLPVS KKTLLCSFQVLDELGRHVLLRKDCG PVDTKVPGAGEPKSAFTQGSAMISS LSQNHPDNRNETFSSVISLLNEDPL SQDLPVKMASIFKNFVITYNRTYES KEEARWRLSVFVNNMVRAQKIQALD RGTAQYGVTKFSDLTEEEFRTIYLN TLLRKEPGNKMKQAKSVGDLAPPEW DWRSKGAVTKVKDQGMCGSCWAFSV TGNVEGQWFLNQGTLLSLSEQELLD CDKMDKACMGGLPSNAYSAIKNLGG LETEDDYSYQGHMQSCNFSAEKAKV YINDSVELSQNEQKLAAWLAKRGPI SVAINAFGMQFYRHGISRPLRPLCS PWLIDHAVLLVGYGNRSDVPFWAIK NSWGTDWGEKGYYYLHRGSGACGVN TMASSAVVD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CTSF cathepsin F [ Homo sapiens ]
Official Symbol : CTSF
Synonyms : CTSF; cathepsin F; CATSF; CLN13;
Gene ID : 8722
mRNA Refseq : NM_003793
Protein Refseq : NP_003784
MIM : 603539
UniProt ID : Q9UBX1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All CTSF Products

Required fields are marked with *

My Review for All CTSF Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends