Recombinant Human CTSH Protein, GST-tagged

• Cat.No.: CTSH-2108H
• Product Overview: Human CTSH full-length ORF ( NP_004381.2, 1 a.a. - 335 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 63.8 kDa
• AA Sequence: MWATLPLLCAGAWLLGVPVCGAAEL CVNSLEKFHFKSWMSKHRKTYSTEE YHHRLQTFASNWRKINAHNNGNHTF KMALNQFSDMSFAEIKHKYLWSEPQ NCSATKSNYLRGTGPYPPSVDWRKK GNFVSPVKNQGACGSCWTFSTTGAL ESAIAIATGKMLSLAEQQLVDCAQD FNNHGCQGGLPSQAFEYILYNKGIM GEDTYPYQGKDGYCKFQPGKAIGFV KDVANITIYDEEAMVEAVALYNPVS FAFEVTQDFMMYRTGIYSSTSCHKT PDKVNHAVLAVGYGEKNGIPYWIVK NSWGPQWGMNGYFLIERGKNMCGLA ACASYPIPLV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CTSH cathepsin H [ Homo sapiens ]
• Official Symbol: CTSH
• Synonyms: CTSH; cathepsin H; CPSB; pro-cathepsin H; ACC 4; ACC 5; aleurain; cathepsin B3; cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; ACC-4; ACC-5; minichain; MGC1519; DKFZp686B24257
• Gene ID: 1512
• mRNA Refseq: NM_004390
• Protein Refseq: NP_004381
• MIM: 116820
• UniProt ID: P09668