Recombinant Human DDX6 protein, MYC/DDK-tagged

• Cat.No.: DDX6-45H
• Product Overview: Recombinant Human DDX6 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 54.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 [ Homo sapiens ]
• Official Symbol: DDX6
• Synonyms: DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp Glu Ala Asp) box polypeptide 6 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase, 54kD) , HLR2; probable ATP-dependent RNA helicase DDX6; RCK; DEAD box-6; oncogene RCK; DEAD box protein 6; ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); P54; HLR2; FLJ36338
• Gene ID: 1656
• mRNA Refseq: NM_004397
• Protein Refseq: NP_004388
• MIM: 600326
• UniProt ID: P26196
• Chromosome Location: 11q23.3
• Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Decapping complex, organism-specific biosystem; Decapping complex, conserved biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; mRNA Decay by 5 to 3 Exoribonuclease, organism-specific biosystem
• Function: ATP binding; ATP-dependent helicase activity; RNA binding; RNA helicase activity; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding; protein binding