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Recombinant Human DHFR protein, His-tagged

Cat.No. : DHFR-42H
Product Overview : Recombinant Human DHFR, fused with N-His tag, was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E.coli
Species : Human
Tag : His
Form : 20mM Tris.Cl, 100mM NaCl, 0.4M Urea, 50% Glycerol, pH8.0.
Molecular Mass : 21.5kDa(including fusion tag)
Protein length : 187aa(including fusion tag)
Applications : WB, ELISA, IP, antibody production, protein array
Storage : Store at -80°C and avoid repeated freeze-thaw cycles
Gene Name : DHFR dihydrofolate reductase [ Homo sapiens ]
Official Symbol : DHFR
Synonyms : DHFR; dihydrofolate reductase; DYR; DHFRP1;
Gene ID : 1719
mRNA Refseq : NM_000791
Protein Refseq : NP_000782
MIM : 126060
UniProt ID : P00374
Chromosome Location : Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; E2F mediated regulation of DNA replication, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you name a common DHFR inhibitor drug used in cancer treatment? 03/12/2020

Methotrexate is a common DHFR inhibitor drug used in cancer treatment.

Are there ongoing research efforts to develop new DHFR inhibitors for clinical use? 02/21/2018

Yes, scientists continue to research and develop new DHFR inhibitors with improved efficacy and reduced side effects for various clinical applications.

Are there any drug-resistant strains that have developed due to DHFR inhibitors? 12/06/2017

Yes, drug-resistant strains have emerged due to mutations in DHFR genes, reducing the effectiveness of DHFR inhibitor drugs.

Are there any side effects associated with DHFR inhibitor drugs like Methotrexate? 11/28/2017

Yes, common side effects of DHFR inhibitors include nausea, vomiting, decreased blood cell counts, and liver toxicity.

Can you name an antibiotic that inhibits DHFR in bacteria? 11/21/2016

Trimethoprim is an antibiotic that inhibits DHFR in bacteria.

Customer Reviews (3)

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Reviews
04/16/2023

    The DHFR protein offered by the manufacturer is of exceptional quality, making it an ideal choice to fulfill my experimental needs.

    03/20/2017

      Another crucial aspect where the manufacturer excels is their efficient supply chain management.

      08/31/2016

        The technical support provided by the manufacturer is invaluable in overcoming experimental hurdles and optimizing the utilization of DHFR protein.

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