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Recombinant Human DKK2 protein, Fc/His-tagged

Cat.No. : DKK2-277H
Product Overview : Recombinant Human DKK2 fused with N-terminal Fc tag and C-terminal His was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Source : HEK293
Species : Human
Tag : Fc/His
Form : Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.2
Molecular Mass : 58.9 kDa
AA Sequence : EPKSCDKTHTCPPCPAPELLGGPSV FLFPPKPKDTLMISRTPEVTCVVVD VSHEDPEVKFNWYVDGVEVHNAKTK PREEQYNSTYRVVSVLTVLHQDWLN GKEYKCKVSNKALPAPIEKTISKAK GQPREPQVYTLPPSREEMTKNQVSL TCLVKGFYPSDIAVEWESNGQPENN YKTTPPVLDSDGSFFLYSKLTVDKS RWQQGNVFSCSVMHEALHNHYTQKS LSLSPGKVDGGGSGGGSGGGSRKRR MAALMRSKDSSCCLLLLAAVLMVES SQIGSSRAKLNSIKSSLGGETPGQA ANRSAGMYQGLAFGGSKKGKNLGQA YPCSSDKECEVGRYCHSPHQGSSAC MVCRRKKKRCHRDGMCCPSTRCNNG ICIPVTESILTPHIPALDGTQHRDR NHGHYSNHDLGWQNLGRPHTKMSHI KGHEGDPCLRSSDCIEGFCCARHFW TKICKPVLHQGEVCTKQRKKGSHGL EIFQRCDCAKGLSCKVWKDATYSSK ARLHVCQKIVDHHHHHH
Endotoxin : Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Name : DKK2 dickkopf 2 homolog (Xenopus laevis) [ Homo sapiens ]
Official Symbol : DKK2
Synonyms : DKK2; dickkopf 2 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 2; dickkopf-related protein 2; hDkk-2; dickkopf-2; dickkopf homolog 2; dickkopf related protein-2; DKK-2;
Gene ID : 27123
mRNA Refseq : NM_014421
Protein Refseq : NP_055236
MIM : 605415
UniProt ID : Q9UBU2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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