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Recombinant Human DLK1 protein, His-tagged

Cat.No. : DLK1-187H
Product Overview : Recombinant human DLK1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : DLK1, also known as protein delta homolog 1, belongs to the Notch/Delta/Serrate family of epidermal growth factor (EGF)-like repeat-containing proteins that act as ligands in the Notch signaling pathway. It has six well conserved epidermal-growth-factor motifs and contains up to ten O-glycosylation and N-glycosylation sites, six of which are differentially glycosylated.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 30.7kDa (288aa)28-40kDa (SDS-PAGE under reducing conditions)
AA Sequence : AECFPACNPQ NGFCEDDNVC RCQPGWQGPL CDQCVTSPGC LHGLCGEPGQ CICTDGWDGE LCDRDVRACS SAPCANNGTC VSLDDGLYECSCAPGYSGKD CQKKDGPCVI NGSPCQHGGT CVDDEGRASH ASCLCPPGFS GNFCEIVANS CTPNPCENDG VCTDIGGDFR CRCPAGFIDKTCSRPVTNCA SSPCQNGGTC LQHTQVSYEC LCKPEFTGLT CVKKRALSPQ QVTRLPSGYG LAYRLTPGVH ELPVQQPEHR ILKVSMKELNKKTPLLTEGQ LEHHHHHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : > 95% by SDS – PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Absorbance at 280nm)
Gene Name : DLK1 delta-like 1 homolog (Drosophila) [ Homo sapiens ]
Official Symbol : DLK1
Synonyms : DLK1; delta-like 1 homolog (Drosophila); delta like homolog (Drosophila); protein delta homolog 1; Delta1; FA1; pG2; Pref 1; ZOG; DLK-1; secredeltin; fetal antigen 1; preadipocyte factor 1; DLK; PREF1; Pref-1;
Gene ID : 8788
mRNA Refseq : NM_003836
Protein Refseq : NP_003827
MIM : 176290
UniProt ID : P80370
Chromosome Location : 14q32
Pathway : Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Adipogenesis, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;
Function : molecular_function;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does DLK1 protein contribute to cell senescence? 11/12/2021

DLK1 has been found to play a role in cellular senescence, and understanding this process may have implications for aging-related research.

Are there ongoing clinical trials involving DLK1 protein? 04/20/2021

Yes, there are clinical trials exploring the therapeutic potential of targeting DLK1 in cancer treatment and regenerative medicine.

How is DLK1 protein linked to adipogenesis? 12/28/2020

DLK1 is involved in the regulation of adipocyte differentiation, and understanding its role may have implications for obesity-related research.

How does DLK1 protein impact stem cell differentiation? 12/08/2020

DLK1 is involved in the regulation of stem cell differentiation, making it a potential target for therapeutic applications in regenerative medicine.

Can manipulating DLK1 expression have therapeutic benefits? 05/21/2019

Modulating DLK1 expression holds promise for therapeutic interventions, such as controlling cell growth in cancer or enhancing tissue regeneration.

Customer Reviews (3)

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Reviews
10/14/2022

    In addition to these experimental benefits, the manufacturer of DLK1 protein plays a vital role in supporting researchers.

    06/15/2022

      DLK1 protein demonstrates exceptional stability and consistency, ensuring reliable and reproducible results throughout the duration of the trial.

      01/24/2018

        DLK1 protein exhibits high bioactivity, enabling efficient and effective interactions with its molecular targets.

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