Recombinant Human DLK1 protein, His-tagged
Cat.No. : | DLK1-187H |
Product Overview : | Recombinant human DLK1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | DLK1, also known as protein delta homolog 1, belongs to the Notch/Delta/Serrate family of epidermal growth factor (EGF)-like repeat-containing proteins that act as ligands in the Notch signaling pathway. It has six well conserved epidermal-growth-factor motifs and contains up to ten O-glycosylation and N-glycosylation sites, six of which are differentially glycosylated. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 30.7kDa (288aa)28-40kDa (SDS-PAGE under reducing conditions) |
AA Sequence : | AECFPACNPQ NGFCEDDNVC RCQPGWQGPL CDQCVTSPGC LHGLCGEPGQ CICTDGWDGE LCDRDVRACS SAPCANNGTC VSLDDGLYECSCAPGYSGKD CQKKDGPCVI NGSPCQHGGT CVDDEGRASH ASCLCPPGFS GNFCEIVANS CTPNPCENDG VCTDIGGDFR CRCPAGFIDKTCSRPVTNCA SSPCQNGGTC LQHTQVSYEC LCKPEFTGLT CVKKRALSPQ QVTRLPSGYG LAYRLTPGVH ELPVQQPEHR ILKVSMKELNKKTPLLTEGQ LEHHHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | > 95% by SDS – PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Absorbance at 280nm) |
Gene Name : | DLK1 delta-like 1 homolog (Drosophila) [ Homo sapiens ] |
Official Symbol : | DLK1 |
Synonyms : | DLK1; delta-like 1 homolog (Drosophila); delta like homolog (Drosophila); protein delta homolog 1; Delta1; FA1; pG2; Pref 1; ZOG; DLK-1; secredeltin; fetal antigen 1; preadipocyte factor 1; DLK; PREF1; Pref-1; |
Gene ID : | 8788 |
mRNA Refseq : | NM_003836 |
Protein Refseq : | NP_003827 |
MIM : | 176290 |
UniProt ID : | P80370 |
Chromosome Location : | 14q32 |
Pathway : | Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Adipogenesis, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem; |
Function : | molecular_function; |
Products Types
◆ Recombinant Protein | ||
Dlk1-2579M | Recombinant Mouse Dlk1 Protein, Myc/DDK-tagged | +Inquiry |
DLK1-001H | Recombinant Human DLK1 Protein, MYC/DDK-tagged | +Inquiry |
Dlk1-2400M | Recombinant Mouse Dlk1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DLK1-2683H | Recombinant Human DLK1 Protein, GST-tagged | +Inquiry |
DLK1-2801H | Recombinant Human DLK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DLK1-6909HCL | Recombinant Human DLK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDLK1 has been found to play a role in cellular senescence, and understanding this process may have implications for aging-related research.
Yes, there are clinical trials exploring the therapeutic potential of targeting DLK1 in cancer treatment and regenerative medicine.
DLK1 is involved in the regulation of adipocyte differentiation, and understanding its role may have implications for obesity-related research.
DLK1 is involved in the regulation of stem cell differentiation, making it a potential target for therapeutic applications in regenerative medicine.
Modulating DLK1 expression holds promise for therapeutic interventions, such as controlling cell growth in cancer or enhancing tissue regeneration.
Customer Reviews (3)
Write a reviewIn addition to these experimental benefits, the manufacturer of DLK1 protein plays a vital role in supporting researchers.
DLK1 protein demonstrates exceptional stability and consistency, ensuring reliable and reproducible results throughout the duration of the trial.
DLK1 protein exhibits high bioactivity, enabling efficient and effective interactions with its molecular targets.
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