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Recombinant Human DLL4 Protein, GST-tagged

Cat.No. : DLL4-2687H
Product Overview : Human DLL4 partial ORF ( NP_061947, 123 a.a. - 221 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.63 kDa
AA Sequence : HAPGDDLRPEALPPDALISKIAIQG SLAVGQNWLLDEQTSTLTRLRYSYR VICSDNYYGDNCSRLCKKRNDHFGH YVCQPDGNLSCLPGWTGEYCQQPI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DLL4 delta-like 4 (Drosophila) [ Homo sapiens ]
Official Symbol : DLL4
Synonyms : DLL4; delta-like 4 (Drosophila); delta like 4 homolog (Drosophila); delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4; hdelta2; MGC126344;
Gene ID : 54567
mRNA Refseq : NM_019074
Protein Refseq : NP_061947
MIM : 605185
UniProt ID : Q9NR61

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What role does DLL4 play in vascular diseases, such as atherosclerosis? 03/27/2023

DLL4 is implicated in the regulation of vascular inflammation and plaque formation, making it a potential target for atherosclerosis treatments.

How does DLL4 contribute to Alzheimer's disease pathogenesis? 10/27/2022

DLL4 has been linked to Alzheimer's disease as it can influence amyloid-beta accumulation and the activation of microglia in the brain.

Can DLL4 be used as a biomarker for any diseases? 10/01/2021

DLL4 levels can serve as a potential biomarker in some diseases, such as certain cancers, where it may indicate disease progression.

What are the challenges in developing DLL4-targeted therapies? 01/20/2018

Challenges include potential side effects, the need for personalized treatment approaches, and the complexity of the Notch signaling pathway.

How does DLL4 affect tissue regeneration? 05/23/2017

DLL4 can modulate tissue regeneration by influencing stem cell behavior and promoting tissue repair processes.

Customer Reviews (3)

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Reviews
07/29/2022

    They ensure a consistent and reliable supply of DLL4 protein, minimizing any potential disruptions in my experimental workflow.

    05/01/2021

      the manufacturer's commitment to scientific collaboration and knowledge sharing greatly enhances my research experience.

      12/09/2017

        This collaborative approach empowers me to integrate cutting-edge knowledge, explore innovative techniques, and expand the impact of my research.

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