Recombinant Human DNM2 protein, His/T7-tagged
Cat.No. : | DNM2-15H |
Product Overview : | Recombinant Human DNM2(aa 533-731) fused with His/T7 tag was expressed in E. coli. |
- Specification
- Gene Information
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Description : | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. |
Source : | E. coli |
Species : | Human |
Tag : | His/T7 |
Form : | Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl |
Molecular Mass : | 27.2 kDa |
Purity : | Greater than 95% |
Storage : | Store at +4 centigradefor up to 1 month, or aliquot and store at -80 centigradefor up to 12 months. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute in sterile PBS, pH 7.2-7.4. |
Publication : |
Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis (2019)
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Gene Name : | DNM2 dynamin 2 [ Homo sapiens ] |
Official Symbol : | DNM2 |
Synonyms : | DNM2; dynamin 2; dynamin-2; CMTDI1; CMTDIB; cytoskeletal protein; DI CMTB; DYN2; dynamin II; DYNII; CMT2M; DI-CMTB; |
Gene ID : | 1785 |
mRNA Refseq : | NM_004945 |
Protein Refseq : | NP_004936 |
MIM : | 602378 |
UniProt ID : | P50570 |
Chromosome Location : | 19p |
Pathway : | Arf6 trafficking events, organism-specific biosystem; Axon guidance, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Clathrin derived vesicle budding, organism-specific biosystem |
Function : | GTP binding; GTPase activity; GTPase activity; enzyme binding; hydrolase activity; microtubule binding; nucleotide binding; protein binding; protein complex binding; protein kinase binding; |
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DNM2-1976H | Recombinant Human DNM2 Protein (Leu533-Glu731), N-His tagged | +Inquiry |
◆ Lysates | ||
DNM2-6857HCL | Recombinant Human DNM2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionDNM2 interacts with β-actin.
DNM2 is closely associated with the study of chronic heart failure and chronic progressive extraocular muscle paralysis in the elderly.
DNM2 gene is widely expressed in various mammalian tissues.
DNM1 and DNM3 are all homologs of DNM2.
DNM2 is involved in the regulation of Golgi reticular system transport, mitochondrial fusion, cytoplasmic division and synaptic vesicle endocytosis.
N-terminal GTPase structural domain, intermediate domain, PH structural domain, GTPase effector structural domain, and C-terminal proline- and arginine-rich domain.
Customer Reviews (3)
Write a reviewDNM2 proteins purchased are as advertised and the quality of the product is guaranteed.
Excellent after-sales service, solving many experimental problems.
The technician gave me a thorough introduction to the DNM2 protein so that I could understand its biochemical properties.
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