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Recombinant Human DOK2 Protein, GST-tagged

Cat.No. : DOK2-2810H
Product Overview : Human DOK2 full-length ORF ( AAH32623, 1 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 71.06 kDa
AA Sequence : MGDGAVKQGFLYLQQQQTFGKKWRR FGASLYGGSDCALARLELQEGPEKP RRCGAARKVIRLSDCLRVAEAGGEA SSPRDTSAFFLETKERLYLLAAPAA ERGDWVQAICLLAFPGQRKELSGPE GKQSRPCMEENELYSSAVTVGPHKE FAVTMRPTEASERCHLRGSYTLRAG ESALELWGGPEPGTQLYDWPYRFLR RFGRDKVTFSFEAGRRCVSGEGNFE FETRQGNEIFLALEEAISAQKNAAP ATPQPQPATIPASLPRPDSPYSRPH DSLPPPSPTTPVPAPRPRGQEGEYA VPFDAVARSLGKNFRGILAVPPQLL ADPLYDSIEETLPPRPDHIYDEPEG VAALSLYDSPQEPRGEAWRRQATAD RDPAGLQHVQPAGQDFSASGWQPGT EYDNVVLKKGPK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DOK2 docking protein 2, 56kDa [ Homo sapiens ]
Official Symbol : DOK2
Synonyms : DOK2; docking protein 2, 56kDa; docking protein 2, 56kD; docking protein 2; Dok 2; p56dok 2; p56(dok-2); downstream of tyrosine kinase 2; p56DOK; p56dok-2;
Gene ID : 9046
mRNA Refseq : NM_003974
Protein Refseq : NP_003965
MIM : 604997
UniProt ID : O60496

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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