Recombinant Human ENO1 protein, His-tagged
Cat.No. : | ENO1-2513H |
Product Overview : | Recombinant Human ENO1(1-434aa) fused with His tag at N-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Description : | This gene encodes one of three enolase isoenzymes found in mammals; it encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. A pseudogene has been identified that is located on the other arm of the same chromosome. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Protein length : | 1-434aa |
AA Sequence : | SILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IGKAGYTDKV VIGMDVAASE FFRSGKYDLD FKSPDDPSRY ISPDQLADLY KSFIKDYPVV SIEDPFDQDD WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AVNEKSCNCL LLKVNQIGSV TESLQACKLA QANGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL LRIEEELGSK AKFAGRNFRN PLAK |
Purity : | >90% ( SDS-PAGE ) |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. |
Gene Name : | ENO1 enolase 1, (alpha) [ Homo sapiens ] |
Official Symbol : | ENO1 |
Synonyms : | ENO1; enolase 1, (alpha); ENO1L1, MPB1; alpha-enolase; c-myc promoter-binding protein-1; MBP 1; PPH; alpha-enolase; enolase-alpha; tau-crystallin; non-neural enolase; alpha enolase like 1; phosphopyruvate hydratase; plasminogen-binding protein; MYC promoter-binding protein 1; 2-phospho-D-glycerate hydro-lyase; NNE; MPB1; ENO1L1; |
Gene ID : | 2023 |
mRNA Refseq : | NM_001201483 |
Protein Refseq : | NP_001188412 |
MIM : | 172430 |
UniProt ID : | P06733 |
Chromosome Location : | 1p36.2 |
Pathway : | Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; |
Function : | DNA binding; lyase activity; magnesium ion binding; phosphopyruvate hydratase activity; protein binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; |
Products Types
◆ Recombinant Protein | ||
ENO1-842H | Recombinant Human ENO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ENO1-0498H | Recombinant Human ENO1 Protein (M1-K434), Tag Free | +Inquiry |
ENO1-2791M | Recombinant Mouse ENO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ENO1-3309H | Recombinant Human ENO1 Protein, GST-tagged | +Inquiry |
ENO1-238C | Recombinant Cynomolgus Monkey ENO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ENO1-6599HCL | Recombinant Human ENO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0324 | ENO1 Human Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionENO1 overexpression is seen in cancers like lung cancer, breast cancer, pancreatic cancer, and glioblastoma, among others.
ENO1 in infectious agents may offer potential targets for diagnostic tests and treatments, although this field of research is still developing.
Some research suggests that targeted therapies directed at ENO1 could be a potential strategy for cancer treatment, but more studies are needed.
ENO1 antibodies can be used as diagnostic markers for autoimmune diseases like celiac disease.
ENO1 may serve as a potential biomarker for the early diagnosis and monitoring of neurodegenerative diseases, although more research is needed.
Customer Reviews (3)
Write a reviewIts ability to bind to negatively charged phospholipids, particularly during blood clot formation, has made it invaluable for in vitro and in vivo investigations of hemostatic mechanisms.
the use of ENO1 protein in my research offers significant advantages in detecting cell death processes and investigating coagulation and thrombosis mechanisms.
The manufacturer of ENO1 protein plays a crucial role in supporting my research endeavors.
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