Active Recombinant Human EPHA3 Protein, GST/His-tagged

• Cat.No.: EPHA3-3380H
• Product Overview: Human EPHA3 (NM_005233, 569 a.a. - 983 a.a.) partial recombinant protein with GST-His tag expressed in Sf9 cells.

Specification

• Description: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
• Source: Insect cells
• Species: Human
• Tag: GST/His
• Form: Liquid
• Bio-activity: 184 pmol/μg x min
• Molecular Mass: 75.680 kDa
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing
• Concentration: 0.140 μg/μL
• Storage Buffer: In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: EPHA3 EPH receptor A3 [ Homo sapiens ]
• Official Symbol: EPHA3
• Synonyms: EPHA3; EPH receptor A3; EphA3 , ETK, ETK1, TYRO4; ephrin type-A receptor 3; HEK; HEK4; EPH-like kinase 4; human embryo kinase 1; eph-like tyrosine kinase 1; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor ETK1; EK4; ETK; ETK1; TYRO4
• Gene ID: 2042
• mRNA Refseq: NM_005233
• Protein Refseq: NP_005224
• MIM: 179611
• UniProt ID: P29320