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Recombinant Human EPHB4 Protein, GST-tagged

Cat.No. : EPHB4-3404H
Product Overview : Human EPHB4 full-length ORF ( AAH52804.1, 1 a.a. - 987 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 134.7 kDa
AA Sequence : MELRVLLCWASLAAALEETLLNTKL ETADLKWVTFPQVDGQWEELSGLDE EQHSVRTYEVCDVQRAPGQAHWLRT GWVPRRGAVHVYATLRFTMLECLSL PRAGRSCKETFTVFYYESDADTATA LTPAWMENPYIKVDTVAAEHLTRKR PGAEATGKVNVRTLRLGPLSKAGFY LAFQDQGACMALLSLHLFYKKCAQL TVNLTRFPETVPRELVVPVAGSCVV DAVPAPGPSPSLYCREDGQWAEQPV TGCSCAPGFEAAEGNTKCRACAQGT FKPLSGEGSCQPCPANSHSNTIGSA VCQCRVGYFRARTDPRGAPCTTPPS APRSVVSRLNGSSLHLEWSAPLESG GREDLTYALRCRECRPGGSCAPCGG DLTFDPGPRDLVEPWVVVRGLRPDF TYTFEVTALNGVSSLATGPVPFEPV NVTTDREVPPAVSDIRVTRSSPSSL SLAWAVPRAPSGAVLDYEVKYHEKG AEGPSSVRFLKTSENRAELRGLKRG ASYLVQVRARSEAGYGPFGQEHHSQ TQLDESEGWREQLALIAGTAVVGVV LVLVVIVVAVLCLRKQSNGREAEYS DKHGQYLIGHGTKVYIDPFTYEDPN EAVREFAKEIDVSYVKIEEVIGAGE FGEVCRGRLKAPGKKESCVAIKTLK GGYTERQRREFLSEASIMGQFEHPN IIRLEGVVTNSMPVMILTEFMENGA LDSFLRLNDGQFTVIQLVGMLRGIA SGMRYLAEMSYVHRDLAARNILVNS NLVCKVSDFGLSRFLEENSSDPTYT SSLGGKIPIRWTAPEAIAFRKFTSA SDAWSYGIVMWEVMSFGERPYWDMS NQDVINAIEQDYRLPPPPDCPTSLH QLMLDCWQKDRNARPRFPQVVSALD KMIRNPASLKIVARENGGASHPLLD QRQPHYSAFGSVGEWLRAIKMGRYE ESFAAAGFGSFELVSQISAEDLLRI GVTLAGHQKKILASVQHMKSQAKPG TPGGTGGPAPQY
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : EPHB4 EPH receptor B4 [ Homo sapiens ]
Official Symbol : EPHB4
Synonyms : EPHB4; EPH receptor B4; EphB4 , HTK; ephrin type-B receptor 4; Tyro11; ephrin receptor EphB4; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; hepatoma transmembrane kinase; tyrosine-protein kinase TYRO11; tyrosine-protein kinase receptor HTK; HTK; MYK1; TYRO11;
Gene ID : 2050
mRNA Refseq : NM_004444
Protein Refseq : NP_004435
MIM : 600011
UniProt ID : P54760

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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