Recombinant Human EPOR protein, His-tagged
Cat.No. : | EPOR-194H |
Product Overview : | Recombinant human EPOR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | EPOR, also known as Erythropoietin receptor, mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, it dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. So it may also activate the LYN tyrosine kinase. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 25.6kDa (232aa)28-40kDa (SDS-PAGE under reducing conditions) |
AA Sequence : | APPPNLPDPK FESKAALLAA RGPEELLCFT ERLEDLVCFW EEAASAGVGP GNYSFSYQLE DEPWKLCRLH QAPTARGAVR FWCSLPTADTSSFVPLELRV TAASGAPRYH RVIHINEVVL LDAPVGLVAR LADESGHVVL RWLPPPETPM TSHIRYEVDV SAGNGAGSVQ RVEILEGRTECVLSNLRGRT RYTFAVRARM AEPSFGGFWS AWSEPVSLLT PSDLDPHHHH HH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | > 95% by SDS – PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | EPOR erythropoietin receptor [ Homo sapiens ] |
Official Symbol : | EPOR |
Synonyms : | EPOR; erythropoietin receptor; EPO-R; MGC138358; |
Gene ID : | 2057 |
mRNA Refseq : | NM_000121 |
Protein Refseq : | NP_000112 |
MIM : | 133171 |
UniProt ID : | P19235 |
Chromosome Location : | 19p13.3-p13.2 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; EPO Receptor Signaling, organism-specific biosystem; EPO signaling pathway, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; |
Function : | erythropoietin receptor activity; identical protein binding; protein binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
EPOR-3424H | Recombinant Human EPOR Protein, GST-tagged | +Inquiry |
EPOR-241H | Recombinant Human EPOR Protein, Fc-tagged | +Inquiry |
Epor-42M | Recombinant Mouse Epor Protein, His (Fc)-Avi-tagged | +Inquiry |
EPOR-1434H | Recombinant Human EPOR Protein, His-tagged | +Inquiry |
EPOR-2045H | Recombinant Human EPOR Protein, Fc/His-tagged | +Inquiry |
◆ Lysates | ||
EPOR-2055HCL | Recombinant Human EPOR cell lysate | +Inquiry |
EPOR-2582MCL | Recombinant Mouse EPOR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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