Recombinant Human ERBB4 Protein, GST-tagged
Cat.No. : | ERBB4-3451H |
Product Overview : | Human ERBB4 full-length ORF (NP_005226.1, 1 a.a. - 1308 a.a.) recombinant protein with GST tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 169.51 kDa |
AA Sequence : | MKPATGLWVWVSLLVAAGTVQPSDS QSVCAGTENKLSSLSDLEQQYRALR KYYENCEVVMGNLEITSIEHNRDLS FLRSVREVTGYVLVALNQFRYLPLE NLRIIRGTKLYEDRYALAIFLNYRK DGNFGLQELGLKNLTEILNGGVYVD QNKFLCYADTIHWQDIVRNPWPSNL TLVSTNGSSGCGRCHKSCTGRCWGP TENHCQTLTRTVCAEQCDGRCYGPY VSDCCHRECAGGCSGPKDTDCFACM NFNDSGACVTQCPQTFVYNPTTFQL EHNFNAKYTYGAFCVKKCPHNFVVD SSSCVRACPSSKMEVEENGIKMCKP CTDICPKACDGIGTGSLMSAQTVDS SNIDKFINCTKINGNLIFLVTGIHG DPYNAIEAIDPEKLNVFRTVREITG FLNIQSWPPNMTDFSVFSNLVTIGG RVLYSGLSLLILKQQGITSLQFQSL KEISAGNIYITDNSNLCYYHTINWT TLFSTINQRIVIRDNRKAENCTAEG MVCNHLCSSDGCWGPGPDQCLSCRR FSRGRICIESCNLYDGEFREFENGS ICVECDPQCEKMEDGLLTCHGPGPD NCTKCSHFKDGPNCVEKCPDGLQGA NSFIFKYADPDRECHPCHPNCTQGC NGPTSHDCIYYPWTGHSTLPQHART PLIAAGVIGGLFILVIVGLTFAVYV RRKSIKKKRALRRFLETELVEPLTP SGTAPNQAQLRILKETELKRVKVLG SGAFGTVYKGIWVPEGETVKIPVAI KILNETTGPKANVEFMDEALIMASM DHPHLVRLLGVCLSPTIQLVTQLMP HGCLLEYVHEHKDNIGSQLLLNWCV QIAKGMMYLEERRLVHRDLAARNVL VKSPNHVKITDFGLARLLEGDEKEY NADGGKMPIKWMALECIHYRKFTHQ SDVWSYGVTIWELMTFGGKPYDGIP TREIPDLLEKGERLPQPPICTIDVY MVMVKCWMIDADSRPKFKELAAEFS RMARDPQRYLVIQGDDRMKLPSPND SKFFQNLLDEEDLEDMMDAEEYLVP QAFNIPPPIYTSRARIDSNRSEIGH SPPPAYTPMSGNQFVYRDGGFAAEQ GVSVPYRAPTSTIPEAPVAQGATAE IFDDSCCNGTLRKPVAPHVQEDSST QRYSADPTVFAPERSPRGELDEEGY MTPMRDKPKQEYLNPVEENPFVSRR KNGDLQALDNPEYHNASNGPPKAED EYVNEPLYLNTFANTLGKAEYLKNN ILSMPEKAKKAFDNPDYWNHSLPPR STLQHPDYLQEYSTKYFYKQNGRIR PIVAENPEYLSEFSLKPGTVLPPPP YRHRNTVV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) [ Homo sapiens ] |
Official Symbol : | ERBB4 |
Synonyms : | ERBB4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v erb a avian erythroblastic leukemia viral oncogene homolog like 4; receptor tyrosine-protein kinase erbB-4; proto-oncogene-like protein c-ErbB-4; tyrosine kinase-type cell surface receptor HER4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; HER4; p180erbB4; MGC138404; |
Gene ID : | 2066 |
mRNA Refseq : | NM_001042599 |
Protein Refseq : | NP_001036064 |
MIM : | 600543 |
UniProt ID : | Q15303 |
Products Types
◆ Recombinant Protein | ||
ERBB4-859H | Recombinant Human ERBB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERBB4-1326S | Recombinant Human ERBB4 Protein (R676-V1308), GST tagged | +Inquiry |
ERBB4-04H | Active Recombinant Human ERBB4 Protein, hIgG/His-tagged | +Inquiry |
ERBB4-1325S | Recombinant Human ERBB4 Protein (R676-V1308), Tag Free | +Inquiry |
Erbb4-7416M | Active Recombinant Mouse Erbb4 Protein, His tagged | +Inquiry |
◆ Lysates | ||
ERBB4-1543HCL | Recombinant Human ERBB4 cell lysate | +Inquiry |
ERBB4-895RCL | Recombinant Rat ERBB4 cell lysate | +Inquiry |
ERBB4-001HCL | Recombinant Human ERBB4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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