Active Recombinant Human EZH2 Complex protein, His/Flag-tagged

• Cat.No.: EZH2-161H
• Product Overview: Recombinant Human EZH2 Complex protein fused with N-terminal His-tag (SUZ12, EZH2, RbAP48), N-terminal FLAG-tag (EED) was co-expressed in Insect cells.

Specification

• Source: Insect cells
• Species: Human
• Tag: His/Flag
• Form: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, and 10% glycerol
• Bio-activity: 0.046 pmol/min/µg
• Molecular Mass: 272 kDa (complex)
• Protein length: 2–end (all components)
• Purity: >95%
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles
• Concentration: 0.6 mg/ml

Gene Information

• Gene Name: EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: EZH2
• Synonyms: EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169
• Gene ID: 2146
• mRNA Refseq: NM_004456
• Protein Refseq: NP_004447
• MIM: 601573
• UniProt ID: Q15910
• Chromosome Location: 7q35-q36
• Function: DNA binding; histone methyltransferase activity; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity