Recombinant Human EZH2 Complex protein, His/Flag-tagged
Cat.No. : | EZH2-164H |
Product Overview : | Mutant version of EZH2 5-member complex, but with a Glu-to-Lys mutation on a.a. 745 of the EZH2 protein.* Complex of human EZH2 (GenBank Accession No. NM_004456), (a.a. 2-end; E745K) with N-terminal His-tag, MW= 86 kDa, human EED (NM_003797) (a.a. 2-end) with N-terminal FLAG-tag, MW= 51 kDa, human SUZ12 (NM_015355) (a.a. 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (NM_153207) (a.a. 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (NM_005610) (a.a. 2-end) with N-terminal His-tag, MW = 48 kDa, co-expressed in a baculovirus expression system. |
- Specification
- Gene Information
- Related Products
Source : | Insect cells |
Species : | Human |
Tag : | His/Flag |
Form : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, and 20% glycerol |
Molecular Mass : | 325 kDa (complex) |
Protein length : | 2–end (all components) |
AA Sequence : | MHHHHHHGQTGKKSEKGPVCWRKRV KSEYMRLRQLKRFRRADEVKSMFSS NRQKILERTEILNQEWKQRRIQPVH ILTSVSSLRGTRECSVTSDLDFPTQ VIPLKTLNAVASVPIMYSWSPLQQN FMVEDETVLHNIPYMGDEVLDQDG TFIEELIKNYDGKVHGDRECGFIND EIFVELVNALGQYNDDDDDDDGDDP EEREEKQKDLEDHRDDKESRPPRKF PSDKIFEAISSMFPDKGTAEELKEK YKELTEQQLPGALPPECTPNIDGPN AKSVQREQSLHSFHTLFCRRCFKY DCFLHRKCNYSFHATPNTYKRKNTE TALDNKPCGPQCYQHLEGAKEFAAA LTAERIKTPPKRPGGRRRGRLPNN SSRPSTPTINVLESKDTDSDREAGT ETGGENNDKEEEEKKDETSSSSEAN SRCQTPIKMKPNIEPPENVEWSGAE ASMFRVLIGTYYDNFCAIARLIGTK TCRQVYEFRVKESSIIAPAPAEDVD TPPRKKKRKHRLWAAHCRKIQLKK DGSSNHVYNYQPCDHPRQPCDSSCP CVIAQNFCEKFCQCSSECQNRFPGC RCKAQCNTKQCPCYLAVRECDPDL CLTCGAADHWDSKNVSCKNCSIQRG SKKHLLLAPSDVAGWGIFIKDPVQK NEFISEYCGEIISQDEADRRGKVYD KYMCSFLFNLNNDFVVDATRKGNKI RFANHSVNPNCYAKVMMVNGDHRIG IFAKRAIQTGEELFFDYRYSQADA LKYVGIKREMEIP |
Purity : | ≥ 81% |
Applications : | Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex. |
Storage : | >6 months at -70 centigrade. Avoid freeze/thaw cycles |
Concentration : | 0.38 mg/ml |
Gene Name : | EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ] |
Official Symbol : | EZH2 |
Synonyms : | EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169; |
Gene ID : | 2146 |
mRNA Refseq : | NM_004456 |
Protein Refseq : | NP_004447 |
MIM : | 601573 |
UniProt ID : | Q15910 |
Chromosome Location : | 7q35-q36 |
Function : | DNA binding; histone methyltransferase activity; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Ezh2-991M | Recombinant Mouse Ezh2 Protein, MYC/DDK-tagged | +Inquiry |
EZH2-1353R | Recombinant Rhesus Macaque EZH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
EZH2-46H | Recombinant Human EZH2 Protein, His-tagged | +Inquiry |
EZH2-879H | Recombinant Human EZH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
EZH2-285H | Recombinant Human EZH2 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
EZH2-6487HCL | Recombinant Human EZH2 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1727 | EZH2 Homogeneous Assay Kit | +Inquiry |
Kit-1725 | EZH2 (Y641N) Chemiluminescent Assay Kit | +Inquiry |
Kit-1726 | EZH2 Chemiluminescent Assay Kit | +Inquiry |
Kit-1723 | EZH2 (A677G) Chemiluminescent Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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