Recombinant Human F10 Protein, GST-tagged
Cat.No. : | F10-3601H |
Product Overview : | Human F10 full-length ORF ( AAH46125, 32 a.a. - 488 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 76.01 kDa |
AA Sequence : | NNILARVTRANSFLEEMKKGHLERE CMEETCSYEEAREVFEDSDKTNEFW NKYKDGDQCETSPCQNQGKCKDGLG EYTCTCLEGFEGKNCELFTRKLCSL DNGDCDQFCHEEQNSVVCSCARGYT LADNGKACIPTGPYPCGKQTLERRK RSVAQATSSSGEAPDSITWKPYDAA DLDPTENPFDLLDFNQTQPERGDNN LTRIVGGQECKDGECPWQALLINEE NEGFCGGTILSEFYILTAAHCLYQA KRFKVRVGDRNTEQEEGGEAVHEVE VVIKHNRFTKETYDFDIAVLRLKTP ITFRMNVAPACLPERDWAESTLMTQ KTGIVSGFGRTHEKGRQSTRLKMLE VPYVDRNSCKLSSSFIITQNMFCAG YDTKQEDACQGDSGGPHVTRFKDTY FVTGIVSWGEGCARKGKYGIYTKVT AFLKWIDRSMKTRGLPKAKSHAPEV ITSSPLK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | F10 coagulation factor X [ Homo sapiens ] |
Official Symbol : | F10 |
Synonyms : | F10; coagulation factor X; factor Xa; prothrombinase; Stuart-Prower factor; FX; FXA; |
Gene ID : | 2159 |
mRNA Refseq : | NM_000504 |
Protein Refseq : | NP_000495 |
MIM : | 613872 |
UniProt ID : | P00742 |
Products Types
◆ Recombinant Protein | ||
F10-1831R | Recombinant Rat F10 Protein, His (Fc)-Avi-tagged | +Inquiry |
F10-908R | Recombinant Rat F10 Protein, His-tagged | +Inquiry |
F10-1354R | Recombinant Rhesus Macaque F10 Protein, His (Fc)-Avi-tagged | +Inquiry |
F10-993M | Recombinant Mouse F10 Protein, MYC/DDK-tagged | +Inquiry |
F10-1447H | Recombinant Human F10 Protein, His&GST-tagged | +Inquiry |
◆ Native Protein | ||
F10-5395R | Active Native Rat Coagulation Factor X | +Inquiry |
F10-63H | Native Human Factor X | +Inquiry |
F10-302R | Native Rat Factor X | +Inquiry |
◆ Lysates | ||
F10-719HCL | Recombinant Human F10 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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