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Recombinant Human FCGRT Protein

Cat.No. : FCGRT-038H
Product Overview : Recombinant human IgG1 Fc (rhIgG1 Fc) Glu99 - Lys330 (Accession # AAC82527.1) was expressed in human 293 cells (HEK293).
  • Specification
  • Gene Information
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Description : This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Source : HEK293 cells
Species : Human
Molecular Mass : rhIgG1 Fc, a 232 amino acids protein, has a calculated MW of 26 kDa. DTT-reduced protein migrates as 35 kDa protein due to glycosylation.
Endotoxin : Less than 1.0 EU per 0.5µg of the human IgG1 Fc by the LAL method.
Purity : >98% as determined by SDS-PAGE of 20 µg reduced rhIgG1 Fc. All lots are greater than 98% pure.
Notes : Research Use Only. Not for use in diagnostic or therapeutic procedures.
Storage : Store at -20 centigrade in lyophilized state after receipt. For long term storage, upon reconstitution rhIgG1 Fc should be aliquot and store at -20 centigrade or -8 centigrade centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : Bulk protein in a 0.22 µm filtered solution of PBS, pH 7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization.
Gene Name : FCGRT Fc fragment of IgG, receptor, transporter, alpha [ Homo sapiens ]
Official Symbol : FCGRT
Synonyms : FCGRT; Fc fragment of IgG, receptor, transporter, alpha; IgG receptor FcRn large subunit p51; alpha chain; FCRN; FcRn alpha chain; neonatal Fc receptor; neonatal Fc-receptor for Ig; IgG Fc fragment receptor transporter alpha chain; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; alpha-chain;
Gene ID : 2217
mRNA Refseq : NM_001136019
Protein Refseq : NP_001129491
MIM : 601437
UniProt ID : P55899

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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10/16/2019

    With a long shelf life, a single bottle of the reagent can be used multiple times, which is especially valuable for budget-conscious laboratories.

    07/24/2019

      It maintains its activity and effectiveness under various environmental conditions.

      04/11/2017

        The reagent has a wide range of applications, catering to diverse needs in different laboratories, be it in biomedical research or the field of bioengineering.

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