Recombinant Human FGD4 Protein, GST-tagged
Cat.No. : | FGD4-4092H |
Product Overview : | Human FGD4 full-length ORF (BAB71413.1, 1 a.a. - 766 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 113 kDa |
AA Sequence : | MEEIKPASASCVSKEKPSKVSDLIS RFEGGSSLSNYSDLKKESAVNLNAP RTPGRHGLTTTPQQKLLSQHLPQRQ GNDADKTQGAQTCVANGVMAAQNQM ECEEEKAATLSSDTSIQASEPLLDT HIVNGERDETATAPASPTTDSCDGN ASDSSYRTPGIGPVLPLEERGAETE TKVQERENGESPLELEQLDQHHEMK ETNEQKLHKIANELLLTERAYVNRL DLLDQVFYCKLLEEANRGSFPAEMV NKIFSNISSINAFHSKFLLPELEKR MQEWETTPRIGDILQKLAPFLKMYG EYVKGFDNAMELVKNMTERIPQFKS VVEEIQKQKICGSLTLQHHMLEPVQ RIPRYEMLLKDYLRKLPPDSLDWND AKKSLEIISTAASHSNSAIRKMENL KKLLEIYEMLGEEEDIVNPSNELIK EGQILKLAARNTSAQERYLFLFNNM LLYCVPKFSLVGSKFTVRTRVGIDG MKIVETQNEEYPHTFQVSGKERTLE LQASSAQDKEEWIKALQETIDAFHQ RHETFRNAIAKDNDIHSEVSTAELG KRAPRWIRDNEVTMCMKCKEPFNAL TRRRHHCRACGYVVCWKCSDYKAQL EYDGGKLSKVCKDCYQIISGFTDSE EKKRKGILEIESAEVSGNSVVCSFL QYMEKSKPWQKAWCVIPKQDPLVLY MYGAPQDVRAQATIPLLGYVVDEMP RSADLPHSFKLTQSKSVHSFAADSE ELKQKWLKVILLAVTGETPGGPNEH PATLDDHPEPKKKSEC |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FGD4 FYVE, RhoGEF and PH domain containing 4 [ Homo sapiens ] |
Official Symbol : | FGD4 |
Synonyms : | FGD4; FYVE, RhoGEF and PH domain containing 4; FGD1 family, member 4; FYVE, RhoGEF and PH domain-containing protein 4; CMT4H; frabin; FRABP; ZFYVE6; FGD1-related F-actin-binding protein; actin-filament binding protein frabin; zinc finger FYVE domain-containing protein 6; FLJ34370; FLJ42663; MGC57222; DKFZp313E1818; DKFZp434K1572; |
Gene ID : | 121512 |
mRNA Refseq : | NM_139241 |
Protein Refseq : | NP_640334 |
MIM : | 611104 |
UniProt ID : | Q96M96 |
Products Types
◆ Recombinant Protein | ||
FGD4-1979R | Recombinant Rat FGD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Fgd4-2992M | Recombinant Mouse Fgd4 Protein, Myc/DDK-tagged | +Inquiry |
FGD4-3222M | Recombinant Mouse FGD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGD4-2322R | Recombinant Rat FGD4 Protein | +Inquiry |
FGD4-5834M | Recombinant Mouse FGD4 Protein | +Inquiry |
◆ Lysates | ||
FGD4-6253HCL | Recombinant Human FGD4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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