Recombinant Human FGF2 protein, His-tagged
Cat.No. : | FGF2-2784H |
Product Overview : | Recombinant Human FGF2 aa. (Phe159~Ser288) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 16&19kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Phe159~Ser288 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >98% |
Characteristic : | The isoelectric point is 9.7. |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Reporter Assays; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | FGF2 fibroblast growth factor 2 [ Homo sapiens (human) ] |
Official Symbol : | FGF2 |
Synonyms : | BFGF; FGFB; FGF-2; HBGF-2; basic fibroblast growth factor bFGF; fibroblast growth factor 2 (basic); heparin-binding growth factor 2; prostatropin; fibroblast growth factor 2 |
Gene ID : | 2247 |
mRNA Refseq : | NM_002006.4 |
Protein Refseq : | NP_001997.5 |
UniProt ID : | P09038 |
Products Types
◆ Recombinant Protein | ||
Fgf2-79M | Recombinant Active Mouse FGF2 Protein, His-tagged(N-ter) | +Inquiry |
FGF2-40B | Active Native Bovine FGF2 Protein | +Inquiry |
FGF2-06B | Recombinant Bovine/Porcine FGF2 Protein | +Inquiry |
FGF2-78P | Recombinant Active Pig FGF2 Protein, His-tagged(N-ter) | +Inquiry |
FGF2-01H | Active Recombinant Heat Stable Human FGF2 Protein, Animal Free | +Inquiry |
◆ Native Protein | ||
FGF2-34B | Active Native Bovine bFGF | +Inquiry |
◆ Lysates | ||
FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
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