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Recombinant Human FN1 protein, T7/His-tagged

Cat.No. : FN1-38H
Product Overview : Recombinant eleventh FN-III domain of Human fibronectin cDNA fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli.
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  • Gene Information
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Source : E. coli
Species : Human
Tag : T7/His
Form : 1.0 mg/ml, sterile-filtered, in PBS.
AA Sequence : MASMTGGQQMGRGHHHHHHGNLYFQ GGEFEIDKPSQMQVTDVQDNSISVK WLPSSSPVTGYRVTTTPKNGPGPTK TKTAGPDQTEMTIEGLQPTVEYVVS VYAQNPSGESQPLVQTAVT
Purity : >90% by SDS-PAGE
Applications : 1. May be used for in vitro human ES lineage specific differentiation regulations study coating with this protein.2. May be used for in vitro protein-protein interaction mapping.3. As antigen for specific antibody production.
Storage : Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 15 days.
Gene Name : FN1 fibronectin 1 [ Homo sapiens ]
Official Symbol : FN1
Synonyms : FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;
Gene ID : 2335
mRNA Refseq : NM_002026
Protein Refseq : NP_002017
MIM : 135600
UniProt ID : P02751
Chromosome Location : 2q34
Pathway : Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem;
Function : collagen binding; extracellular matrix structural constituent; heparin binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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which organs and tissues is the FN1 protein expressed? 12/21/2019

It is expressed in a variety of organs and tissues, including skin, kidneys, cardiovascular system, liver, etc.

How about the FN1 protein in inflammatory diseases? 09/09/2019

FN1 protein is involved in the migration, adhesion and activation of inflammatory cells during the inflammatory response, and plays an important role in the development of inflammation.

Have regulators of the FN1 protein been identified? 07/16/2019

Yes, multiple factors have been found to regulate the expression and function of FN1 protein, including transcription factors, growth factors, etc.

What is the relationship between FN1 protein and tumor metastasis? 06/26/2019

FN1 protein is involved in the invasion and metastasis of tumor cells, which can provide matrix support and guide signals to promote the migration and invasion of tumor cells.

What is the role of FN1 protein in wound healing? 04/15/2019

This protein is involved in key steps such as fibrosis, angiogenesis and interstitial cell proliferation in the wound healing process, and plays an important role in wound repair.

How about the mechanism of action of FN1 protein in tissue repair? 04/13/2019

The protein plays an important role in key steps such as extracellular matrix remodeling, cell adhesion, and directed differentiation of mesenchymal stem cells during tissue repair.

Customer Reviews (3)

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Reviews
06/21/2021

    The preservation conditions are wide and the efficiency is high.

    08/14/2019

      Experimental process is convenient, which greatly improves the efficiency of scientific research.

      03/25/2019

        Biological activity of this protein is amazing, and you can see that its production process is very pure, which has a crucial effect on the quality of the product.

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