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Active Recombinant Human FOLH1 protein, His-tagged

Cat.No. : FOLH1-2416H
Product Overview : Recombinant Human FOLH1 protein(Lys 44 - Ala 750), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : His
Form : Supplied as 0.2 μm filtered solution in MES and NaCl with trehalose as protectant.
Bio-activity : Immobilized Monoclonal Anti-Human PSMA Antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Human PSMA, His Tag with a linear range of 2-39 ng/mL. Immobilized Human PSMA, His Tag at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human PSMA Antibody, Human IgG1 with a linear range of 0.3-39 ng/mL.Measured by its ability to hydrolyze the substrate N-acetyl-L-Asp-L-Glu into N-acetyl-L-Asp and L-Glu. The L-Glu product is measured by fluorescence after its derivatization by ortho-phthaldialdehyde. The specific activity is >400 pmol/min/μg, as measured under the described conditions.
Molecular Mass : This protein carries a polyhistidine tag at the N-terminus.The protein has a calculated MW of 81.4 kDa. The protein migrates as 95-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein Length : Lys 44 - Ala 750
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 [ Homo sapiens ]
Official Symbol : FOLH1
Synonyms : FOLH1; folate hydrolase (prostate-specific membrane antigen) 1; FOLH; glutamate carboxypeptidase 2; GCP2; GCPII; glutamate carboxylase II; glutamate carboxypeptidase II; NAALAD1; NAALAdase; PSM; PSMA; NAALADase I; membrane glutamate carboxypeptidase; cell growth-inhibiting gene 27 protein; folylpoly-gamma-glutamate carboxypeptidase; prostate specific membrane antigen variant F; pteroylpoly-gamma-glutamate carboxypeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; FGCP; mGCP;
Gene ID : 2346
mRNA Refseq : NM_001014986
Protein Refseq : NP_001014986
MIM : 600934
UniProt ID : Q04609

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What advancements have been made in FOLH1-targeted therapies recently? 03/16/2021

New radioligands and imaging agents with enhanced specificity and reduced off-target effects are being developed for more effective treatment.

How does targeting FOLH1 impact treatment precision? 01/27/2021

Targeting FOLH1 helps deliver treatments directly to cancer cells, minimizing damage to healthy tissues, thus improving treatment precision.

Are there other potential applications of FOLH1 beyond prostate cancer? 03/16/2018

Yes, research suggests potential roles in imaging and therapy for other cancers expressing FOLH1, such as renal cell carcinoma and certain types of gliomas.

Can FOLH1 be used for early cancer detection? 11/19/2017

Yes, FOLH1-based imaging techniques show promise in detecting cancer at early stages, aiding in timely intervention and improved outcomes.

Are there ongoing clinical trials exploring FOLH1's applications? 03/25/2016

Yes, numerous trials investigate FOLH1-targeted imaging and therapies in various cancers, aiming to expand its clinical utility.

Customer Reviews (3)

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Reviews
09/05/2019

    It has been shown to play a crucial role in multiple cellular processes, making it highly valuable for investigations into cell signaling, inflammation, and immune responses.

    01/28/2018

      Incorporating the FOLH1 protein into your research will not only meet but exceed your expectations, enabling you to advance your scientific discoveries with confidence.

      06/06/2016

        Researchers can leverage the unique properties of the FOLH1 protein to gain insights into its biological functions and its impact on disease mechanisms.

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