Recombinant Human GHRL Protein, GST-tagged

• Cat.No.: GHRL-4892H
• Product Overview: Human GHRL full-length ORF ( AAH25791.1, 1 a.a. - 117 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 38.61 kDa
• AA Sequence: MPSPGTVCSLLLLGMLWLDLAMAGS SFLSPEHQRVQQRKESKKPPAKLQP RALAGWLRPEDGGQAEGAEDEMEVR FNAPFDVGIKLSGVQYQQHSQALGK FLQDILWEEAKEAPADK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GHRL ghrelin/obestatin prepropeptide [ Homo sapiens ]
• Official Symbol: GHRL
• Synonyms: GHRL; ghrelin/obestatin prepropeptide; ghrelin, growth hormone secretagogue receptor ligand; appetite-regulating hormone; ghrelin; MTLRP; obestatin; motilin-related peptide; growth hormone secretagogue; ghrelin/obestatin preprohormone; growth hormone-releasing peptide
• Gene ID: 51738
• mRNA Refseq: NM_001134941
• Protein Refseq: NP_001128413
• MIM: 605353
• UniProt ID: Q9UBU3