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Recombinant Human GPD1 protein, His-tagged

Cat.No. : GPD1-17H
Product Overview : Recombinant Human GPD1(Met1-Met349) fused with His tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : Glycerol-3-Phosphate Dehydrogenase [NAD(+)], Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH); they have different substrates.
Source : HEK293
Species : Human
Tag : His
Form : Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 10% Glycerol, pH 8.0.
AA Sequence : MASKKVCIVGSGNWGSAIAKIVGGN AAQLAQFDPRVTMWVFEEDIGGKKL TEIINTQHENVKYLP GHKLPPNVVAVPDVVQAAEDADILI FVVPHQFIGKICDQLKGHLKANATG ISLIKGVDEGPNGLK LISEVIGERLGIPMSVLMGANIASE VADEKFCETTIGCKDPAQGQLLKEL MQTPNFRITVVQEVD TVEICGALKNVVAVGAGFCDGLGFG DNTKAAVIRLGLMEMIAFAKLFCSG PVSSATFLESCGVAD LITTCYGGRNRKVAEAFARTGKSIE QLEKELLNGQKLQGPETARELYSIL QHKGLVDKFPLFMAV YKVCYEGQPVGEFIHCLQNHPEHMV DHHHHHH
Endotoxin : Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Storage : Store at < -20 centigrade, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Gene Name : GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) [ Homo sapiens ]
Official Symbol : GPD1
Synonyms : GPD1; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerophosphate dehydrogenase; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; GPD-C; HTGTI; GPDH-C; FLJ26652;
Gene ID : 2819
mRNA Refseq : NM_001257199
Protein Refseq : NP_001244128
MIM : 138420
UniProt ID : P21695
Chromosome Location : 12q13.12
Pathway : Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Triacylglyceride Synthesis, organism-specific biosystem; Triglyceride Biosynthesis, organism-specific biosystem;
Function : NAD binding; glycerol-3-phosphate dehydrogenase [NAD+] activity; glycerol-3-phosphate dehydrogenase activity; protein homodimerization activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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