Description : |
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010] |
Source : |
Wheat Germ |
Species : |
Human |
Form : |
Liquid |
Molecular Mass : |
67.4 kDa |
AA Sequence : |
MGPTLAVPTPYGCIGCKLPQPEYPP ALIIFMFCAMVITIVVDLIGNSMVI LAVTKNKKLRNSGNIFVVSLSVADM LVAIYPYPLMLHAMSIGGWDLSQLQ CQMVGFITGLSVVGSIFNIVAIAIN RYCYICHSLQYERIFSVRNTCIYLV ITWIMTVLAVLPNMYIGTIEYDPRT YTCIFNYLNNPVFTVTIVCIHFVLP LLIVGFCYVRIWTKVLAARDPAGQN PDNQLAEVRNFLTMFVIFLLFAVCW CPINVLTVLVAVSPKEMAGKIPNWL YLAAYFIAYFNSCLNAVIYGLLNEN FRREYWTIFHAMRHPIIFFSGLISD IREMQEARTLARARAHARDQAREQD RAHACPAVEETPMNVRNVPLPGDAA AGHPDRASGHPKPHSRSSSAYRKSA STHHKSVFSHSKAASGHLKPVSGHS KPASGHPKSATVYPKPASVHFKADS VHFKGDSVHFKPDSVHFKPASSNPK PITGHHVSAGSHSKSAFSAATSHPK PTTGHIKPATSHAEPTTADYPKPAT TSHPKPTAADNPELSASHCPEIPAI AHPVSDDSDLPESASSPAAGPTKPA ASQLESDTIADLPDPTVVTTSTNDY HDVVVVDVEDDPDEMAV |
Applications : |
Antibody Production Functional Study Compound Screening |
Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
Notes : |
Best use within three months from the date of receipt of this protein. |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |