Recombinant Human GRM4 Protein
Cat.No. : | GRM4-5367H |
Product Overview : | Human GRM4 full-length ORF (ADR83416.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 100.4 kDa |
AA Sequence : | MPGKRGLGWWWARLPLCLLLSLYGP WMPSSLGKPKGHPHMNSIRIDGDIT LGGLFPVHGRGSEGKPCGELKKEKG IHRLEAMLFALDRINNDPDLLPNIT LGARILDTCSRDTHALEQSLTFVQA LIEKDGTEVRCGSGGPPIITKPERV VGVIGASGSSVSIMVANILRLFKIP QISYASTAPDLSDNSRYDFFSRVVP SDTYQAQAMVDIVRALKWNYVSTVA SEGSYGESGVEAFIQKSREDGGVCI AQSVKIPREPKAGEFDKIIRRLLET SNARAVIIFANEDDIRRVLEAARRA NQTGHFFWMGSDSWGSKIAPVLHLE EVAEGAVTILPKRMSVRGFDRYFSS RTLDNNRRNIWFAEFWEDNFHCKLS RHALKKGSHVKKCTNRERIGQDSAY EQEGKVQFVIDAVYAMGHALHAMHR DLCPGRVGLCPRMDPVDGTQLLKYI RNVNFSGIAGNPVTFNENGDAPGRY DIYQYQLRNDSAEYKVIGSWTDHLH LRIERMHWPGSGQQLPRSICSLPCQ PGERKKTVKGMPCCWHCEPCTGYQY QVDRYTCKTCPYDMRPTENRTGCRP IPIIKLEWGSPWAVLPLFLAVVGIA ATLFVVITFVRYNDTPIVKASGREL SYVLLAGIFLCYATTFLMIAEPDLG TCSLRRIFLGLGMSISYAALLTKTN RIYRIFEQGKRSVSAPRFISPASQL AITFSLISLQLLGICVWFVVDPSHS VVDFQDQRTLDPRFARGVLKCDISD LSLICLLGYSMLLMVTCTVYAIKTR GVPETFNEAKPIGFTMYTTCIVWLA FIPIFFGTSQSADKLYIQTTTLTVS VSLSASVSLGMLYMPKVYIILFHPE QNVPKRKRSLKAVVTAATMSNKFTQ KGNFRPNGEAKSELCENLEAPALAT KQTYVTYTNHAI |
Applications : | Antibody Production Functional Study Compound Screening |
Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | GRM4 glutamate receptor, metabotropic 4 [ Homo sapiens ] |
Official Symbol : | GRM4 |
Synonyms : | GRM4; glutamate receptor, metabotropic 4; metabotropic glutamate receptor 4; GPRC1D; mGlu4; MGLUR4; MGC177594; |
Gene ID : | 2914 |
mRNA Refseq : | NM_000841 |
Protein Refseq : | NP_000832 |
MIM : | 604100 |
UniProt ID : | Q14833 |
Products Types
◆ Recombinant Protein | ||
GRM4-3942M | Recombinant Mouse GRM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRM4-313C | Recombinant Cynomolgus Monkey GRM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRM4-2370R | Recombinant Rat GRM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRM4-567C | Recombinant Cynomolgus GRM4 Protein, His-tagged | +Inquiry |
GRM4-7287M | Recombinant Mouse GRM4 Protein | +Inquiry |
◆ Lysates | ||
GRM4-5734HCL | Recombinant Human GRM4 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1335 | cAMP GRM4 CHO-K1 GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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