Recombinant Human GSK3A Protein, GST-tagged

• Cat.No.: GSK3A-4397H
• Product Overview: Human GSK3A full-length ORF (AAH27984.1, 1 a.a. - 483 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Glycogen synthase kinase 3-alpha (GSK3A; EC {2.7.1.37}) is a multifunctional protein serine kinase, homologous to Drosophila shaggy (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (see GYS1, {138570}) and transcription factors (e.g., JUN, {165160}). It also plays a role in the WNT ({164820}) and PI3K (see PIK3CG, {601232}) signaling pathways (see review by {1:Ali et al. (2001)}).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.4 kDa
• AA Sequence: MSGGGPSGGGPGGSGRARTSSFAEP GGGGGGGGGGPGGSASGPGGTGGGK ASVGAMGGGVGASSSGGGPGGSGGG GSGGPGAGTSFPPPGVKLGRDSGKV TTVVATLGQGPERSQEVAYTDIKVI GNGSFGVVYQARLAETRELVAIKKV LQDKRFKNRELQIMRKLDHCNIVRL RYFFYSSGEKKDELYLNLVLEYVPE TVYRVARHFTKAKLTIPILYVKVYM YQLFRSLAYIHSQGVCHRDIKPQNL LVDPDTAVLKLCDFGSAKQLVRGEP NVSYICSRYYRAPELIFGATDYTSS IDVWSAGCVLAELLLGQPIFPGDSG VDQLVEIIKVLGTPTREQIREMNPN YTEFKFPQIKAHPWTKVFKSRTPPE AIALCSSLLEYTPSSRLSPLEACAH SFFDELRCLGTQLPNNRPLPPLFNF SAGELSIQPSLNAILIPPHLRSPAG TTTLTPSSQALTETPTSSDWQSTDA TPTLTNSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GSK3A glycogen synthase kinase 3 alpha [ Homo sapiens ]
• Official Symbol: GSK3A
• Synonyms: GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A; DKFZp686D0638
• Gene ID: 2931
• mRNA Refseq: NM_019884
• Protein Refseq: NP_063937
• MIM: 606784
• UniProt ID: P49840