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Recombinant Human H2AFY Protein, HIS-tagged

Cat.No. : H2AFY-133H
Product Overview : Recombinant Human H2AFY, transcript variant 4, fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : E. coli
Species : Human
Tag : HIS
Form : 50mM Tris, 8M Urea, pH8.0.
Molecular Mass : 39.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : H2AFY H2A histone family, member Y [ Homo sapiens ]
Official Symbol : H2AFY
Synonyms : H2AFY; H2A histone family, member Y; core histone macro-H2A.1; macroH2A1.2; histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; medulloblastoma antigen MU-MB-50.205; H2A.y; H2A/y; H2AFJ; mH2A1; H2AF12M; MACROH2A1.1;
Gene ID : 9555
mRNA Refseq : NM_001040158
Protein Refseq : NP_001035248
MIM : 610054
UniProt ID : O75367

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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