Recombinant Human HABP2 protein, GST-tagged

• Cat.No.: HABP2-20H
• Product Overview: Recombinant Human HABP2(C-term-389aa) fused with GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 100 mM GSH, pH 8.0) and 10% glycerol.
• Protein length: C-term-389aa
• AA Sequence: SKFTCACPDQFKGKFCEIGSDDCYV GDGYSYRGKMNRTVNQHACLYWNSH LLLQENYNMFMEDAETHGIGEHNFC RNPDADEKPWCFIKVTNDKVKWEYC DVSACSAQDVAYPEESPTEPSTKLP GFDSCGKTEIAERKIKRIYGGFKST AGKHPWQASLQSSLPLTISMPQGHF CGGALIHPCWVLTAAHCTDIKTRHL KVVLGDQDLKKEEFHEQSFRVEKIF KYSHYNERDEIPHNDIALLKLKPVD GHCALESKYVKTVCLPDGSFPSGSE CHISGWGVTETGKGSRQLLDAKVKL IANTLCNSRQLYDHMIDDSMICAGN LQKPGQDTCQGDSGGPLTCEKDGTY YVYGIVSWGLECGKRPGVYTQVTKF LNWIKATIKSESGF
• Storage: Aliquot and store at -20 centigrade to -80 centigrade for up to 6 months. Avoid freeze thaw cycles.

Gene Information

• Gene Name: HABP2 hyaluronan binding protein 2 [ Homo sapiens ]
• Official Symbol: HABP2
• Synonyms: HABP2; hyaluronan binding protein 2; hyaluronan-binding protein 2; factor VII activating protein; FSAP; HABP; HGFAL; PHBP; plasma hyaluronan binding protein; factor VII-activating protease; factor seven-activating protease; hyaluronic acid binding protein 2; plasma hyaluronan-binding protein; hepatocyte growth factor activator-like protein
• Gene ID: 3026
• mRNA Refseq: NM_001177660
• Protein Refseq: NP_001171131
• MIM: 603924
• UniProt ID: Q14520
• Chromosome Location: 10q25.3
• Function: glycosaminoglycan binding; peptidase activity; serine-type endopeptidase activity