Active Recombinant Human HCK Protein, GST-His-tagged

• Cat.No.: HCK-4625H
• Product Overview: Human HCK (NM_002110, 1 a.a. - 505 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.

Specification

• Description: The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. [provided by RefSeq
• Source: Insect Cell
• Species: Human
• Tag: GST-His
• Form: Liquid
• Bio-activity: 34 pmol/μg x min
• Molecular Mass: 86.707 kDa
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 0.143 μg/μL
• Storage Buffer: In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: HCK hemopoietic cell kinase [ Homo sapiens ]
• Official Symbol: HCK
• Synonyms: HCK; hemopoietic cell kinase; tyrosine-protein kinase HCK; JTK9; p59-HCK/p60-HCK; hematopoietic cell kinase; p59Hck; p61Hck
• Gene ID: 3055
• mRNA Refseq: NM_001172129
• Protein Refseq: NP_001165600
• MIM: 142370
• UniProt ID: P08631