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Recombinant Human HDAC3 Protein, GST-tagged

Cat.No. : HDAC3-4643H
Product Overview : Human HDAC3 full-length ORF ( AAH00614, 1 a.a. - 428 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 72.82 kDa
AA Sequence : MAKTVAYFYDPDVGNFHYGAGHPMK PHRLALTHSLVLHYGLYKKMIVFKP YQASQHDMCRFHSEDYIDFLQRVSP TNMQGFTKSLNAFNVGDDCPVFPGL FEFCSRYTGASLQGATQLNNKICDI AINWAGGLHHAKKFEASGFCYVNDI VIGILELLKYHPRVLYIDIDIHHGD GVQEAFYLTDRVMTVSFHKYGNYFF PGTGDMYEVGAESGRYYCLNVPLRD GIDDQSYKHLFQPVINQVVDFYQPT CIVLQCGADSLGCDRLGCFNLSIRG HGECVEYVKSFNIPLLVLGGGGYTV RNVARCWTYETSLLVEEAISEELPY SEYFEYFAPDFTLHPDVSTRIENQN SRQYLDQIRQTIFENLKMLNHAPSV QIHDVPADLLTYDRTDEADAEERGP EENYSRPEAPNEFYDGDHDNDKESD VEI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : HDAC3 histone deacetylase 3 [ Homo sapiens ]
Official Symbol : HDAC3
Synonyms : HDAC3; histone deacetylase 3; HD3; RPD3; RPD3 2; SMAP45; RPD3-2;
Gene ID : 8841
mRNA Refseq : NM_003883
Protein Refseq : NP_003874
MIM : 605166
UniProt ID : O15379

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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