Recombinant Human HEMK1 protein, GST-tagged

• Cat.No.: HEMK1-186H
• Product Overview: Recombinant Human HEMK1 fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: HEMK1 belongs to the HemK methyltransferase family, members of which are found in genomes from bacteria to humans. HEMK1 methylates the glutamine residue in the GGQ motif of HMRF1L, a human mitochondrial release factor, and plays an important regulatory role in translation termination process.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: 65 kDa
• Applications: Methyltransferase Assay
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: HEMK1 HemK methyltransferase family member 1 [ Homo sapiens ]
• Official Symbol: HEMK1
• Synonyms: HEMK1; HemK methyltransferase family member 1; hemK methyltransferase family member 1; MTQ1; m.HsaHemKP; HEMK homolog 7kb; HEMK; FLJ22320
• Gene ID: 51409
• mRNA Refseq: NM_016173
• Protein Refseq: NP_057257
• UniProt ID: Q9Y5R4
• Chromosome Location: 3p21
• Pathway: Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem; Tyrosine metabolism, organism-specific biosystem; Tyrosine metabolism, conserved biosystem
• Function: DNA binding; N-methyltransferase activity; protein methyltransferase activity; transferase activity