Active Recombinant Human HGF Protein
Cat.No. : | HGF-4728H |
Product Overview : | Human HGF (heterodimer) (P14210, alpha chain 463 amino acids, beta chain 234 amino acids) recombinant protein expressed in Hi-5 cells. |
- Specification
- Gene Information
- Related Products
Description : | Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq |
Source : | Insect Cell |
Species : | Human |
Form : | Lyophilized |
Bio-activity : | The ED50 determined by the scattering activity in the MDCK cell assay is typically at 0.5-1.0 ng/mL. |
Molecular Mass : | 78 kDa |
Endotoxin : | < 0.1 ng/μg |
Purity : | >= 98% by SDS-PAGE and HPLC |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -2 centigrade on dry atmosphere. After reconstitution with sterilized water, store at -2 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | Lyophilized from 50 mM acetic acid |
Gene Name : | HGF hepatocyte growth factor (hepapoietin A; scatter factor) [ Homo sapiens ] |
Official Symbol : | HGF |
Synonyms : | HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39 , DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen; scatter factor; SF; hepatopoeitin-A; hepatopoietin-A; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; F-TCF; DFNB39; |
Gene ID : | 3082 |
mRNA Refseq : | NM_000601 |
Protein Refseq : | NP_000592 |
MIM : | 142409 |
UniProt ID : | P14210 |
Products Types
◆ Recombinant Protein | ||
HGF-3402M | Active Recombinant Mouse HGF protein(Met1-Leu728) | +Inquiry |
HGF-114H | Recombinant Active Human HGF Protein, Tag Free | +Inquiry |
Hgf-1237R | Recombinant Rat Hgf Protein, GST-tagged | +Inquiry |
Hgf-8664M | Active Recombinant Mouse Hgf protein(Met1-Leu728), His-tagged | +Inquiry |
Hgf-257M | Recombinant Mouse Hgf Protein | +Inquiry |
◆ Native Protein | ||
HGF-38P | Native Porcine HGF | +Inquiry |
HGF-29231TH | Native Human HGF | +Inquiry |
◆ Lysates | ||
HGF-1077CCL | Recombinant Cynomolgus HGF cell lysate | +Inquiry |
HGF-1210MCL | Recombinant Mouse HGF cell lysate | +Inquiry |
HGF-1233RCL | Recombinant Rat HGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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