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Recombinant Human HLA-G protein, His-tagged

Cat.No. : HLA-G-38H
Product Overview : Recombinant Human HLA-G(25 to 338) fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : 38 kDa
AA Sequence : GSHSMRYFSAAVSRPGRGEPRFIAM GYVDDTQFVRFDSDSACPRMEPRAP WVEQEGPEYWEEETRNTKAHAQTDR MNLQTLRGYYNQSEASSHTLQWMIG CDLGSDGRLLRGYEQYAYDGKDYLA LNEDLRSWTAADTAAQISKRKCEAA NVAEQRRAYLEGTCVEWLHRYLENG KEMLQRADPPKTHVTHHPVFDYEAT LRCWALGFYPAEIILTWQRDGEDQT QDVELVETRPAGDGTFQKWAAVVVP SGEEQRYTCHVQHEGLPEPLMLRWK QSSLPTIPIMGIVAGLVVLAAVVTG AAVAAVLWRKKSSD
Purity : > 95 % by SDS-PAGE.
Storage : Store at -80 centigrade.
Concentration : 20 µg at 0.2 mg/ml
Gene Name : HLA-G major histocompatibility complex, class I, G [ Homo sapiens ]
Official Symbol : HLA-G
Synonyms : HLA-G; major histocompatibility complex, class I, G; HLA G histocompatibility antigen, class I, G; HLA class I histocompatibility antigen, alpha chain G; b2 microglobulin; HLA G antigen; HLA class I molecule; MHC class I antigen G; HLA-G histocompatibility antigen, class I, G; MHC-G;
Gene ID : 3135
mRNA Refseq : NM_002127
Protein Refseq : NP_002118
MIM : 142871
UniProt ID : P17693
Chromosome Location : 6p21.3
Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem;
Function : MHC class I receptor activity; protein homodimerization activity; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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