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Recombinant Human HNRNPM protein, His-tagged

Cat.No. : HNRNPM-5432H
Product Overview : Recombinant Human HNRNPM, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Mass : 73.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration : >50 ug/mL as determined by microplate BCA method
Publication :
Cohesin regulates alternative splicing (2023)
Gene Name : HNRNPM heterogeneous nuclear ribonucleoprotein M [ Homo sapiens ]
Official Symbol : HNRNPM
Synonyms : HNRNPM; heterogeneous nuclear ribonucleoprotein M; HNRPM, NAGR1; CEA receptor; CEAR; HNRNPM4; HNRPM4; HTGR1; hnRNA-binding protein M4; N-acetylglucosamine receptor 1; heterogenous nuclear ribonucleoprotein M4; HNRPM; NAGR1; hnRNP M; DKFZp547H118;
Gene ID : 4670
mRNA Refseq : NM_031203
Protein Refseq : NP_112480
MIM : 160994
UniProt ID : P52272
Chromosome Location : 19p13.3-p13.2
Pathway : Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem;
Function : RNA binding; nucleic acid binding; nucleotide binding; protein binding; protein domain specific binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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In which cellular compartments is HNRNPM predominantly located? 10/19/2021

HNRNPM is primarily located in the nucleus but can shuttle between the nucleus and cytoplasm.

How does HNRNPM influence RNA splicing? 03/03/2021

It binds to pre-mRNA, influencing splice site selection and alternative splicing.

What role does HNRNPM play in alternative splicing? 02/27/2021

It regulates alternative splicing by binding to specific RNA sequences.

Are there known genetic mutations that impact HNRNPM function? 08/08/2020

Mutations and altered expression of HNRNPM have been linked to various cancers.

What is the primary role of HNRNPM in cellular processes? 06/20/2020

HNRNPM is involved in RNA processing, including splicing, transport, and stability.

What research methods are commonly used to study HNRNPM? 11/15/2019

Common research methods include RNA immunoprecipitation, western blot, and functional assays.

How is HNRNPM implicated in cancer progression? 01/24/2019

HNRNPM can promote cancer progression by altering splicing to produce oncogenic isoforms.

Customer Reviews (3)

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Reviews
04/24/2022

    Excellent in biochemical assays.

    10/29/2020

      Satisfied, product as described.

      03/11/2019

        Great for scientific research.

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