Recombinant Human HNRNPM protein, His-tagged
Cat.No. : | HNRNPM-5432H |
Product Overview : | Recombinant Human HNRNPM, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Molecular Mass : | 73.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Publication : |
Cohesin regulates alternative splicing (2023)
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Gene Name : | HNRNPM heterogeneous nuclear ribonucleoprotein M [ Homo sapiens ] |
Official Symbol : | HNRNPM |
Synonyms : | HNRNPM; heterogeneous nuclear ribonucleoprotein M; HNRPM, NAGR1; CEA receptor; CEAR; HNRNPM4; HNRPM4; HTGR1; hnRNA-binding protein M4; N-acetylglucosamine receptor 1; heterogenous nuclear ribonucleoprotein M4; HNRPM; NAGR1; hnRNP M; DKFZp547H118; |
Gene ID : | 4670 |
mRNA Refseq : | NM_031203 |
Protein Refseq : | NP_112480 |
MIM : | 160994 |
UniProt ID : | P52272 |
Chromosome Location : | 19p13.3-p13.2 |
Pathway : | Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem; |
Function : | RNA binding; nucleic acid binding; nucleotide binding; protein binding; protein domain specific binding; |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionHNRNPM is primarily located in the nucleus but can shuttle between the nucleus and cytoplasm.
It binds to pre-mRNA, influencing splice site selection and alternative splicing.
It regulates alternative splicing by binding to specific RNA sequences.
Mutations and altered expression of HNRNPM have been linked to various cancers.
HNRNPM is involved in RNA processing, including splicing, transport, and stability.
Common research methods include RNA immunoprecipitation, western blot, and functional assays.
HNRNPM can promote cancer progression by altering splicing to produce oncogenic isoforms.
Customer Reviews (3)
Write a reviewExcellent in biochemical assays.
Satisfied, product as described.
Great for scientific research.
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