Recombinant Human HOOK1 Protein, GST-tagged

• Cat.No.: HOOK1-4928H
• Product Overview: Human HOOK1 full-length ORF ( NP_056972.1, 1 a.a. - 728 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 111 kDa
• AA Sequence: MEETQPPPQPKLPLCDSLMIWLQTF NTASPCQDVKQLTSGVAMAQVLHQI DAAWFNESWLSRIKEDVGDNWRIKA SNVKKVLQGIMSYYHEFLGQQISEA LIPDLNQITECSDPVELGRLLQLIL GCAINCEKKQEHIQNIMTLEESVQH VVMTAIQELMSKEILSSPPNDAVGE LEQQLKRALEELQEALAEKEELRQR CEELDMQVTTLQDEKNSLVSENEMM NEKLDQLDGSFDDPNTVVAKKYFHA QLQLEQLQEENFRLEAAKDDYRVHC EELEKQLIEFQHRNDELTSLAEETR ALKDEIDVLRATSDKANKLESTVEI YRQKLQDLNDLRKQVKTLQETNMMY MHNTVSLEEELKKANAARTQLETYK RQVQDLHVKLSSESKRADTLAFEMK RLEEKHEALLKEKERLIEQRDTLKE TNEELRCSQVQQDHLNQTDASATKS YENLAAEIMPVEYREVFIRLQHENK MLRLQQEGSENERIEELQEQLEQKH RKMNELETEQRLSKERIRELQQQIE DLQKSLQEQGSKSEGESSSKLKQKL EAHMEKLTEVHEELQKKQELIEDLQ PDINQNVQKINELEAALQKKDEDMK AMEERYKMYLEKARNVIKTLDPKLN PASAEIMLLRKQLAEKERRIEILES ECKVAKFRDYEEKLIVSAWYNKSLA FQKLGMESRLVSGGGACSDTGACTP ARSFLAQQRHITNTRRNLSVKVPAT TSD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HOOK1 hook homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: HOOK1
• Synonyms: HOOK1; hook homolog 1 (Drosophila); protein Hook homolog 1; HK1; hHK1; h-hook1; MGC10642
• Gene ID: 51361
• mRNA Refseq: NM_015888
• Protein Refseq: NP_056972
• MIM: 607820
• UniProt ID: Q9UJC3