Recombinant Human HSPD1 Protein, GST-tagged

• Cat.No.: HSPD1-5264H
• Product Overview: Human HSPD1 full-length ORF ( AAH02676.1, 1 a.a. - 573 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 88.77 kDa
• AA Sequence: MLRLPTVFRQMRPVSRVLAPHLTRA YAKDVKFGADARALMLQGVDLLADA VAVTMGPKGRTVIIEQSWGSPKVTK DGVTVAKSIDLKDKYKNIGAKLVQD VANNTNEEAGDGTTTATVLARSIAK EGFEKISKGANPVEIRRGVMLAVDA VIAELKKQSKPVTTPEEIAQVATIS ANGDKEIGNIISDAMKKVGRKGVIT VKDGKTLNDELEIIEGMKFDRGYIS PYFINTSKGQKCEFQDAYVLLSEKK ISSIQSIVPALEIANAHRKPLVIIA EDVDGEALSTLVLNRLKVGLQVVAV KAPGFGDNRKNQLKDMAIATGGAVF GEEGLTLNLEDVQPHDLGKVGEVIV TKDDAMLLKGKGDKAQIEKRIQEII EQLDVTTSEYEKEKLNERLAKLSDG VAVLKVGGTSDVEVNEKKDRVTDAL NATRAAVEEGIVLGGGCALLRCIPA LDSLTPANEDQKIGIEIIKRTLKIP AMTIAKNAGVEGSLIVEKIMQSSSE VGYDAMAGDFVNMVEKGIIDPTKVV RTALLDAAGVASLLTTAEVVVTEIP KEEKDPGMGAMGGMGGGMGGGMF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HSPD1 heat shock 60kDa protein 1 (chaperonin) [ Homo sapiens ]
• Official Symbol: HSPD1
• Synonyms: HSPD1; heat shock 60kDa protein 1 (chaperonin); heat shock 60kD protein 1 (chaperonin) , spastic paraplegia 13 (autosomal dominant) , SPG13; 60 kDa heat shock protein, mitochondrial; GROEL; HSP60; chaperonin 60; 60 kDa chaperonin; heat shock protein 65; P60 lymphocyte protein; mitochondrial matrix protein P1; short heat shock protein 60 Hsp60s1; HLD4; CPN60; HSP65; SPG13; HSP-60; HuCHA60
• Gene ID: 3329
• mRNA Refseq: NM_002156
• Protein Refseq: NP_002147
• MIM: 118190
• UniProt ID: P10809