Active Recombinant Human IL11 Protein
Cat.No. : | IL11-953H |
Product Overview : | Recombinant Human IL11(Pro22-Leu199) was expressed in Pichia Pastoris. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Source : | Pichia Pastoris |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 2% Glycine, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Bio-activity : | ED50 is less than 0.2 ng/ml as determined by the dose-dependent stimulation of murine 7TD1 proliferation. Specific Activity of 8.0 x 10⁶ IU/ mg. |
Molecular Mass : | 19.1 kDa |
Endotoxin : | < 0.1 EU per µg protein as determined by LAL test |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Resuspend the protein to the desired concentration in proper buffer. |
Gene Name : | IL11 interleukin 11 [ Homo sapiens ] |
Official Symbol : | IL11 |
Synonyms : | IL11; interleukin 11; interleukin-11; adipogenesis inhibitory factor; AGIF; IL 11; oprelvekin; IL-11; |
Gene ID : | 3589 |
mRNA Refseq : | NM_000641 |
Protein Refseq : | NP_000632 |
MIM : | 147681 |
UniProt ID : | P20809 |
Products Types
◆ Recombinant Protein | ||
IL11-175H | Active Recombinant Human IL11 Protein (Pro22-Leu199), N-His tagged, Animal-free, Carrier-free | +Inquiry |
IL11-1305C | Recombinant Cynomolgus IL11 protein(Phe22-Leu199) | +Inquiry |
IL11-259I | Active Recombinant Human IL11 Protein | +Inquiry |
IL11-137H | Recombinant Active Human IL11 Protein, His-tagged(N-ter) | +Inquiry |
Il11-182I | Active Recombinant Mouse Il11 Protein | +Inquiry |
◆ Lysates | ||
IL11-5249HCL | Recombinant Human IL11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (10)
Ask a questionTransgenic mice and knockdown models explore IL11's impact on tissue regeneration.
Site-directed mutagenesis identifies key residues in IL11's interaction with IL11RA.
Chromatin immunoprecipitation and DNA methylation analysis decipher IL11's regulatory mechanisms.
Proteomics identifies IL11-interacting proteins and potential cross-talk partners.
Cell-based and luciferase reporter assays elucidate IL11's JAK-STAT signaling activation.
RNA sequencing uncovers IL11-induced gene expression changes across different cell types.
X-ray crystallography and NMR spectroscopy reveal structural details of the IL11-IL11RA complex.
Confocal and super-resolution microscopy visualize IL11 localization in tissues.
Techniques like surface plasmon resonance measure IL11-IL11RA binding affinity and kinetics.
CRISPR screening unveils genes and pathways influenced by IL11 signaling.
Customer Reviews (3)
Write a reviewPotent in bone regeneration models.
Suitable for cell culture.
High yield in expression.
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