Active Recombinant Human IL1B Protein
| Cat.No. : | IL1B-132H |
| Product Overview : | Recombinant human IL-1beta (117-269aa) without tag was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Description : | Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1alpha and IL-1beta. IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. |
| Source : | E. coli |
| Species : | Human |
| Form : | Liquid |
| Bio-activity : | Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is less or euqal to 0.005 ng/ml. |
| Molecular Mass : | 17 kDa |
| AA Sequence : | MAPVRSLNCTLRDSQQKSLVMSGPY ELKALHLQGQDMEQQVVFSMSFVQG EESNDKIPVALGLKEKNLYLSCVLK DDKPTLQLESVDPKNYPKKKMEKRF VFNKIEINNKLEFESAQFPNWYIST SQAENMPVFLGGTKGGQDITDFTMQ FVSS |
| Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
| Purity : | > 95% by SDS-PAGE |
| Storage : | Can be stored at 4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : | 1 mg/mL (determined by BCA assay) |
| Storage Buffer : | PBS pH7.4 |
| Gene Name : | IL1B |
| Official Symbol : | IL1B interleukin 1 beta [ Homo sapiens (human) ] |
| Synonyms : | IL1B; interleukin 1 beta; IL-1; IL1F2; IL1-BETA; interleukin-1 beta; IL-1 beta; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta |
| Gene ID : | 3553 |
| mRNA Refseq : | NM_000576 |
| Protein Refseq : | NP_000567 |
| MIM : | 147720 |
| UniProt ID : | P01584 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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